CHEBI:76130 - difenpiramide

ChEBI IDCHEBI:76130
ChEBI Namedifenpiramide
Stars
DefinitionA monocarboxylic acid amide obtained by formal condensation of the carboxy group from biphenyl-4-ylacetic acid with the amino group of 2-aminopyridine. Used for treatment of rheumatoid arthritis.
Last Modified22 February 2017
SubmitterSteve
DownloadsMolfile
FormulaC19H16N2O
Net Charge0
Average Mass288.350
Monoisotopic Mass288.12626
SMILESO=C(Cc1ccc(-c2ccccc2)cc1)Nc1ccccn1
InChIInChI=1S/C19H16N2O/c22-19(21-18-8-4-5-13-20-18)14-15-9-11-17(12-10-15)16-6-2-1-3-7-16/h1-13H,14H2,(H,20,21,22)
InChIKeyPWHROYKAGRUWDQ-UHFFFAOYSA-N
Wikipedia
Roles Classification
Biological Role:
non-narcotic analgesic  A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors.
Applications:
antipyretic  A drug that prevents or reduces fever by lowering the body temperature from a raised state. An antipyretic will not affect the normal body temperature if one does not have fever. Antipyretics cause the hypothalamus to override an interleukin-induced increase in temperature. The body will then work to lower the temperature and the result is a reduction in fever.
non-narcotic analgesic  A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors.
non-steroidal anti-inflammatory drug  An anti-inflammatory drug that is not a steroid. In addition to anti-inflammatory actions, non-steroidal anti-inflammatory drugs have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins.
ChEBI Ontology
Outgoing Relation(s)
difenpiramide (CHEBI:76130) has functional parent biphenyl-4-ylacetic acid (CHEBI:31597)
difenpiramide (CHEBI:76130) has role antipyretic (CHEBI:35493)
difenpiramide (CHEBI:76130) has role non-narcotic analgesic (CHEBI:35481)
difenpiramide (CHEBI:76130) has role non-steroidal anti-inflammatory drug (CHEBI:35475)
difenpiramide (CHEBI:76130) is a biphenyls (CHEBI:22888)
difenpiramide (CHEBI:76130) is a monocarboxylic acid amide (CHEBI:29347)
difenpiramide (CHEBI:76130) is a pyridines (CHEBI:26421)
IUPAC Name 
2-(biphenyl-4-yl)-N-(pyridin-2-yl)acetamide
Synonyms  Source
N-2-Pyridinyl-(1,1'-biphenyl)-4-acetamideChemIDplus
N-Pyridin-2-yl(1,1'-biphenyl)-4-acetamideChemIDplus
DiphenpyramideChemIDplus
2-Biphenylyl-N-pyridylacetamideChemIDplus
Manual XrefsDatabases
C17720KEGG COMPOUND
DifenpiramideWikipedia
919DrugCentral
Registry NumbersSources
Reaxys:483768Reaxys
CAS:51484-40-3KEGG DRUG
CAS:51484-40-3ChemIDplus
CAS:51484-40-3KEGG COMPOUND
Citations