CHEBI:75592 - L-cycloserine

ChEBI IDCHEBI:75592
ChEBI NameL-cycloserine
Stars
ASCII NameL-cycloserine
DefinitionA 4-amino-1,2-oxazolidin-3-one that has S configuration. An antibiotic isolated from Erwinia uredovora.
Last Modified25 February 2016
SubmitterGareth Owen
DownloadsMolfile
FormulaC3H6N2O2
Net Charge0
Average Mass102.093
Monoisotopic Mass102.04293
SMILES[H][C@]1(N)CONC1=O
InChIInChI=1S/C3H6N2O2/c4-2-1-7-5-3(2)6/h2H,1,4H2,(H,5,6)/t2-/m0/s1
InChIKeyDYDCUQKUCUHJBH-REOHCLBHSA-N
Roles Classification
Chemical Role:
Bronsted base  A molecular entity capable of accepting a hydron from a donor (Brønsted acid).
Biological Roles:
anti-HIV agent  An antiviral agent that destroys or inhibits the replication of the human immunodeficiency virus.
EC 2.3.1.50 (serine C-palmitoyltransferase) inhibitor  An EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor that interferes with the action of serine palmitoyltransferase (EC 2.3.1.50).
Application:
anticonvulsant  A drug used to prevent seizures or reduce their severity.
ChEBI Ontology
Outgoing Relation(s)
L-cycloserine (CHEBI:75592) has role anti-HIV agent (CHEBI:64946)
L-cycloserine (CHEBI:75592) has role anticonvulsant (CHEBI:35623)
L-cycloserine (CHEBI:75592) has role EC 2.3.1.50 (serine C-palmitoyltransferase) inhibitor (CHEBI:59647)
L-cycloserine (CHEBI:75592) is a 4-amino-1,2-oxazolidin-3-one (CHEBI:23503)
L-cycloserine (CHEBI:75592) is enantiomer of D-cycloserine (CHEBI:40009)
Incoming Relation(s)
DL-cycloserine (CHEBI:27792) has part L-cycloserine (CHEBI:75592)
D-cycloserine (CHEBI:40009) is enantiomer of L-cycloserine (CHEBI:75592)
IUPAC Name 
(4S)-4-amino-1,2-oxazolidin-3-one
INNs  Source
levcycloserinumChemIDplus
levcicloserinaChemIDplus
levcycloserineChemIDplus
levcyclosérineWHO MedNet
Synonyms  Source
(S)-4-amino-isoxazolidin-3-oneChEBI
L-4-aminoisoxazolidin-3-oneChEBI
(S)-(−)-cycloserineChemIDplus
(−)-cycloserineChEBI
L-CSChEBI
(4S)-4-aminoisoxazolidin-3-oneIUPAC
Manual XrefsDatabases
HMDB0014405HMDB
CPD-2483MetaCyc
D04706KEGG DRUG
DB00260DrugBank
LSM-5639LINCS
Registry NumbersSources
Reaxys:80799Reaxys
CAS:339-72-0ChemIDplus
Citations