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CHEBI:75391 - hydroxy-2-naphthalenyl-methyl phosphonic acid trisacetoxymethylester

ChEBI IDCHEBI:75391
ChEBI Namehydroxy-2-naphthalenyl-methyl phosphonic acid trisacetoxymethylester
Stars
DefinitionAn organic phosphonate that is the trisacetoxymethylester derivative of naphthalene substituted hydroxymethylphosphonic acid. It has been found to inhibit insulin receptor tyrosine kinase activity and insulin stimulated glucose oxidation.
Last Modified25 February 2016
Submitternamrata
DownloadsMolfile
FormulaC20H23O10P
Net Charge0
Average Mass454.368
Monoisotopic Mass454.10288
SMILESCC(=O)OCOC(c1ccc2ccccc2c1)P(=O)(OCOC(C)=O)OCOC(C)=O
InChIInChI=1S/C20H23O10P/c1-14(21)25-11-28-20(19-9-8-17-6-4-5-7-18(17)10-19)31(24,29-12-26-15(2)22)30-13-27-16(3)23/h4-10,20H,11-13H2,1-3H3
InChIKeyUQODAZKXEREJLZ-UHFFFAOYSA-N
Roles Classification
Biological Role:
tyrosine kinase inhibitor  Any protein kinase inhibitor that interferes with the action of tyrosine kinase.
ChEBI Ontology
Outgoing Relation(s)
hydroxy-2-naphthalenyl-methyl phosphonic acid trisacetoxymethylester (CHEBI:75391) has functional parent hydroxymethylphosphonic acid (CHEBI:5810)
hydroxy-2-naphthalenyl-methyl phosphonic acid trisacetoxymethylester (CHEBI:75391) has role tyrosine kinase inhibitor (CHEBI:38637)
hydroxy-2-naphthalenyl-methyl phosphonic acid trisacetoxymethylester (CHEBI:75391) is a acetate ester (CHEBI:47622)
hydroxy-2-naphthalenyl-methyl phosphonic acid trisacetoxymethylester (CHEBI:75391) is a naphthalenes (CHEBI:25477)
hydroxy-2-naphthalenyl-methyl phosphonic acid trisacetoxymethylester (CHEBI:75391) is a organic phosphonate (CHEBI:37592)
Synonyms  Source
3-[(acetyloxy)methoxy]-4-(naphthalen-2-yl)-3-oxido-8-oxo-2,5,7-trioxa-3λ5-phosphanon-1-yl acetateChEBI
HNMPA-(AM)3ChEBI
Manual XrefsDatabases
LSM-6443LINCS
Registry NumbersSources
Reaxys:11322049Reaxys
Citations