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CHEBI:74767 - Pro-Hyp

ChEBI IDCHEBI:74767
ChEBI NamePro-Hyp
Stars
DefinitionA dipeptide composed of L-proline and L-hydroxyproline residues. It is a biomarker for bone collagen degradation.
Secondary ChEBI IDCHEBI:74516
Last Modified13 October 2016
Submittermwilliams, Steve
DownloadsMolfile
FormulaC10H16N2O4
Net Charge0
Average Mass228.248
Monoisotopic Mass228.11101
SMILESO=C(O)[C@@H]1C[C@@H](O)CN1C(=O)[C@@H]1CCCN1
InChIInChI=1S/C10H16N2O4/c13-6-4-8(10(15)16)12(5-6)9(14)7-2-1-3-11-7/h6-8,11,13H,1-5H2,(H,15,16)/t6-,7+,8+/m1/s1
InChIKeyONPXCLZMBSJLSP-CSMHCCOUSA-N
Species of MetaboliteComponentSourceComments
Homo sapiens (ncbitaxon:9606) - PubMed (12636053)
Roles Classification
Chemical Role:
Bronsted base  A molecular entity capable of accepting a hydron from a donor (Brønsted acid).
Biological Role:
human metabolite  Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens).
Applications:
diagnostic agent  A substance administered to aid diagnosis of a disease.
biomarker  A substance used as an indicator of a biological state.
ChEBI Ontology
Outgoing Relation(s)
Pro-Hyp (CHEBI:74767) has functional parent trans-4-hydroxy-L-proline (CHEBI:18095)
Pro-Hyp (CHEBI:74767) has functional parent L-proline (CHEBI:17203)
Pro-Hyp (CHEBI:74767) has role biomarker (CHEBI:59163)
Pro-Hyp (CHEBI:74767) has role diagnostic agent (CHEBI:33295)
Pro-Hyp (CHEBI:74767) has role human metabolite (CHEBI:77746)
Pro-Hyp (CHEBI:74767) is a dipeptide (CHEBI:46761)
Pro-Hyp (CHEBI:74767) is tautomer of Pro-Hyp zwitterion (CHEBI:133733)
Incoming Relation(s)
Pro-Hyp zwitterion (CHEBI:133733) is tautomer of Pro-Hyp (CHEBI:74767)
IUPAC Name 
L-prolyl-(4R)-4-hydroxy-L-proline
Synonyms  Source
L-Pro-L-HypChEBI
L-Prolyl-L-hydroxyprolineHMDB
ProlylhydroxyprolineHMDB
Manual XrefsDatabases
HMDB0006695HMDB
Registry NumbersSources
Reaxys:21943Reaxys
CAS:18684-24-7HMDB
Citations