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CHEBI:746867 - Remibrutinib

ChEBI IDCHEBI:746867
ChEBI NameRemibrutinib
Stars
DefinitionA small molecule Bruton's tyrosine kinase (BTK) inhibitor, indicated for the treatment of chronic spontaneous urticaria in adults.
Last Modified16 October 2025
SubmitterAnneNiknejad
DownloadsMolfile
FormulaC27H27F2N5O3
Net Charge0
Average Mass507.541
Monoisotopic Mass507.20820
SMILESC=CC(=O)N(C)CCOc1c(N)ncnc1-c1cc(F)cc(NC(=O)c2ccc(C3CC3)cc2F)c1C
InChIInChI=1S/C27H27F2N5O3/c1-4-23(35)34(3)9-10-37-25-24(31-14-32-26(25)30)20-12-18(28)13-22(15(20)2)33-27(36)19-8-7-17(11-21(19)29)16-5-6-16/h4,7-8,11-14,16H,1,5-6,9-10H2,2-3H3,(H,33,36)(H2,30,31,32)
InChIKeyCUABMPOJOBCXJI-UHFFFAOYSA-N
Roles Classification
Biological Role:
tyrosine kinase inhibitor  Any protein kinase inhibitor that interferes with the action of tyrosine kinase.
ChEBI Ontology
Outgoing Relation(s)
Remibrutinib (CHEBI:746867) has role tyrosine kinase inhibitor (CHEBI:38637)
Remibrutinib (CHEBI:746867) is a monofluorobenzenes (CHEBI:83575)
Remibrutinib (CHEBI:746867) is a secondary carboxamide (CHEBI:140325)
Brand Name  Source
RhapsidoKEGG DRUG
Manual XrefsDatabases
D12285KEGG DRUG
Registry NumbersSources
CAS:1787294-07-8KEGG DRUG