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CHEBI:7449 - nafenopin
| ChEBI ID | CHEBI:7449 |
| ChEBI Name | nafenopin |
| Stars | |
| Definition | A racemate comprising equimolar amounts of (R)- and (S)-nafenopin. It is a peroxisome proliferator that is used experimentally to promote liver tumors. It has been used as an hypolipidemic agent. |
| Last Modified | 11 March 2014 |
| Wikipedia |
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| Roles Classification |
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| Biological Roles: | carcinogenic agent A role played by a chemical compound which is known to induce a process of carcinogenesis by corrupting normal cellular pathways, leading to the acquistion of tumoral capabilities. PPARalpha agonist A PPAR modulator which activates the peroxisome proliferator-activated receptor-α. |
| Application: | antilipemic drug A substance used to treat hyperlipidemia (an excess of lipids in the blood). |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| nafenopin (CHEBI:7449) has part (R)-nafenopin (CHEBI:77650) |
| nafenopin (CHEBI:7449) has part (S)-nafenopin (CHEBI:77651) |
| nafenopin (CHEBI:7449) has role antilipemic drug (CHEBI:35679) |
| nafenopin (CHEBI:7449) has role carcinogenic agent (CHEBI:50903) |
| nafenopin (CHEBI:7449) has role PPARα agonist (CHEBI:70782) |
| nafenopin (CHEBI:7449) is a racemate (CHEBI:60911) |
| IUPAC Name |
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| rac-2-methyl-2-[4-(1,2,3,4-tetrahydronaphthalen-1-yl)phenoxy]propanoic acid |
| INNs | Source |
|---|---|
| nafenopinum | WHO MedNet |
| nafenopin | WHO MedNet |
| nafenopina | WHO MedNet |
| nafénopine | WHO MedNet |
| Synonyms | Source |
|---|---|
| 2-methyl-2-[p-(1,2,3,4-tetrahydronaphthalen-1-yl)phenoxy]propionic acid | ChemIDplus |
| SU-13437 | ChemIDplus |
| Ciba 13437 SU | ChemIDplus |
| CH 13437 | ChemIDplus |
| α-methyl-α-(p-1,2,3,4-tetrahydronaphth-1-ylphenoxy)propionic acid | ChemIDplus |
| CH 13-437 | ChemIDplus |
| Brand Names | Source |
|---|---|
| Melipan | ChemIDplus |
| SU 13437 | ChemIDplus |
| Citations |
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