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CHEBI:74125 - losartan carboxylic acid

ChEBI IDCHEBI:74125
ChEBI Namelosartan carboxylic acid
Stars
DefinitionA biphenylyltetrazole that is losartan with the hydroxymethyl group at position 5 on the imidazole ring replaced with a carboxylic acid.
Last Modified28 July 2014
Submittermwilliams
DownloadsMolfile
FormulaC22H21ClN6O2
Net Charge0
Average Mass436.903
Monoisotopic Mass436.14145
SMILESCCCCc1nc(Cl)c(C(=O)O)n1Cc1ccc(-c2ccccc2-c2nnnn2)cc1
InChIInChI=1S/C22H21ClN6O2/c1-2-3-8-18-24-20(23)19(22(30)31)29(18)13-14-9-11-15(12-10-14)16-6-4-5-7-17(16)21-25-27-28-26-21/h4-7,9-12H,2-3,8,13H2,1H3,(H,30,31)(H,25,26,27,28)
InChIKeyZEUXAIYYDDCIRX-UHFFFAOYSA-N
Roles Classification
Biological Role:
metabolite  Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
ChEBI Ontology
Outgoing Relation(s)
losartan carboxylic acid (CHEBI:74125) has functional parent losartan (CHEBI:6541)
losartan carboxylic acid (CHEBI:74125) has role metabolite (CHEBI:25212)
losartan carboxylic acid (CHEBI:74125) is a biphenylyltetrazole (CHEBI:48420)
losartan carboxylic acid (CHEBI:74125) is a imidazoles (CHEBI:24780)
losartan carboxylic acid (CHEBI:74125) is a organochlorine compound (CHEBI:36683)
IUPAC Name 
2-butyl-4-chloro-1-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-imidazole-5-carboxylic acid
Synonym  Source
EXP 3174KEGG COMPOUND
Manual XrefsDatabases
C15554KEGG COMPOUND
Registry NumbersSources
Reaxys:6164851Reaxys
CAS:124750-92-1ChemIDplus
CAS:124750-92-1KEGG COMPOUND