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CHEBI:73261 - 4-(methylamino)antipyrine
| Formula | C12H15N3O |
| Net Charge | 0 |
| Average Mass | 217.272 |
| Monoisotopic Mass | 217.12151 |
| SMILES | CNc1c(C)n(C)n(-c2ccccc2)c1=O |
| InChI | InChI=1S/C12H15N3O/c1-9-11(13-2)12(16)15(14(9)3)10-7-5-4-6-8-10/h4-8,13H,1-3H3 |
| InChIKey | JILCEWWZTBBOFS-UHFFFAOYSA-N |
| Roles Classification |
|---|
| Chemical Role: | Bronsted base A molecular entity capable of accepting a hydron from a donor (Brønsted acid). |
| Biological Roles: | opioid analgesic A narcotic or opioid substance, synthetic or semisynthetic agent producing profound analgesia, drowsiness, and changes in mood. non-narcotic analgesic A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors. EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor A compound or agent that combines with cyclooxygenases (EC 1.14.99.1) and thereby prevents its substrate-enzyme combination with arachidonic acid and the formation of icosanoids, prostaglandins, and thromboxanes. |
| Applications: | non-steroidal anti-inflammatory drug An anti-inflammatory drug that is not a steroid. In addition to anti-inflammatory actions, non-steroidal anti-inflammatory drugs have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. opioid analgesic A narcotic or opioid substance, synthetic or semisynthetic agent producing profound analgesia, drowsiness, and changes in mood. peripheral nervous system drug A drug that acts principally at one or more sites within the peripheral neuroeffector systems, the autonomic system, and motor nerve-skeletal system. non-narcotic analgesic A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors. antipyretic A drug that prevents or reduces fever by lowering the body temperature from a raised state. An antipyretic will not affect the normal body temperature if one does not have fever. Antipyretics cause the hypothalamus to override an interleukin-induced increase in temperature. The body will then work to lower the temperature and the result is a reduction in fever. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| 4-(methylamino)antipyrine (CHEBI:73261) has functional parent antipyrine (CHEBI:31225) |
| 4-(methylamino)antipyrine (CHEBI:73261) has role antipyretic (CHEBI:35493) |
| 4-(methylamino)antipyrine (CHEBI:73261) has role drug metabolite (CHEBI:49103) |
| 4-(methylamino)antipyrine (CHEBI:73261) has role EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor (CHEBI:35544) |
| 4-(methylamino)antipyrine (CHEBI:73261) has role non-narcotic analgesic (CHEBI:35481) |
| 4-(methylamino)antipyrine (CHEBI:73261) has role non-steroidal anti-inflammatory drug (CHEBI:35475) |
| 4-(methylamino)antipyrine (CHEBI:73261) has role opioid analgesic (CHEBI:35482) |
| 4-(methylamino)antipyrine (CHEBI:73261) has role peripheral nervous system drug (CHEBI:49110) |
| 4-(methylamino)antipyrine (CHEBI:73261) is a pyrazoles (CHEBI:26410) |
| 4-(methylamino)antipyrine (CHEBI:73261) is a secondary amino compound (CHEBI:50995) |
| IUPAC Name |
|---|
| 1,5-dimethyl-4-(methylamino)-2-phenyl-1,2-dihydro-3H-pyrazol-3-one |
| Synonyms | Source |
|---|---|
| noraminopyrine | ChemIDplus |
| 4-monomethylaminophenazone | ChemIDplus |
| 4-methylaminoantipyrine | ChEBI |
| 4-methylaminophenazone | ChemIDplus |
| noramidopyrine | ChemIDplus |
| 4-monomethylaminoantipyrine | ChemIDplus |
| Registry Numbers | Sources |
|---|---|
| Reaxys:195234 | Reaxys |
| CAS:519-98-2 | ChemIDplus |
| Citations |
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