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CHEBI:71428 - procarbazine hydrochloride

ChEBI IDCHEBI:71428
ChEBI Nameprocarbazine hydrochloride
Stars
DefinitionA hydrochloride obtained by combining procarbazine with one equivalent of hydrochloric acid. An antineoplastic chemotherapy drug used for treatment of Hodgkin's lymphoma. Metabolism yields azo-procarbazine and hydrogen peroxide, which results in the breaking of DNA strands.
Secondary ChEBI IDCHEBI:8433
Last Modified12 December 2012
SubmitterSteve
DownloadsMolfile
FormulaC12H19N3O.HCl
Net Charge0
Average Mass257.765
Monoisotopic Mass257.12949
SMILESCNNCc1ccc(C(=O)NC(C)C)cc1.Cl
InChIInChI=1S/C12H19N3O.ClH/c1-9(2)15-12(16)11-6-4-10(5-7-11)8-14-13-3;/h4-7,9,13-14H,8H2,1-3H3,(H,15,16);1H
InChIKeyDERJYEZSLHIUKF-UHFFFAOYSA-N
Roles Classification
Application:
antineoplastic agent  A substance that inhibits or prevents the proliferation of neoplasms.
ChEBI Ontology
Outgoing Relation(s)
procarbazine hydrochloride (CHEBI:71428) has part procarbazine(1+) (CHEBI:71431)
procarbazine hydrochloride (CHEBI:71428) has role antineoplastic agent (CHEBI:35610)
procarbazine hydrochloride (CHEBI:71428) is a hydrochloride (CHEBI:36807)
IUPAC Name 
N-(1-methylethyl)-4-[(2-methylhydrazino)methyl]benzamide hydrochloride
Synonyms  Source
1-Methyl-2-(p-isopropylcarbamoylbenzyl)hydrazine hydrochlorideChemIDplus
procarbazine monohydrochlorideChEBI
N-Isopropyl-alpha-(2-methylhydrazino)-p-toluamide hydrochlorideChemIDplus
1-(p-Isopropylcarbamoylbenzyl)-2-methylhydrazine hydrochlorideChemIDplus
N-Isopropyl-p-(2-methylhydrazinomethyl)benzamide hydrochlorideChemIDplus
Procarbazine HClChemIDplus
Manual XrefsDatabases
C07376KEGG COMPOUND
D00478KEGG DRUG
DB01168DrugBank
WO2008100985Patent
WO2005072705Patent
GB2480472Patent
Registry NumbersSources
Reaxys:4024454Reaxys
CAS:366-70-1KEGG COMPOUND
CAS:366-70-1ChemIDplus
Citations