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CHEBI:71320 - cyclopeptine
| Formula | C17H16N2O2 |
| Net Charge | 0 |
| Average Mass | 280.327 |
| Monoisotopic Mass | 280.12118 |
| SMILES | CN1C(=O)c2ccccc2NC(=O)C1Cc1ccccc1 |
| InChI | InChI=1S/C17H16N2O2/c1-19-15(11-12-7-3-2-4-8-12)16(20)18-14-10-6-5-9-13(14)17(19)21/h2-10,15H,11H2,1H3,(H,18,20) |
| InChIKey | KSQNKZMAMGACTL-UHFFFAOYSA-N |
| Roles Classification |
|---|
| Biological Role: | GABA modulator A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act. |
| Application: | GABA modulator A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| cyclopeptine (CHEBI:71320) is a 1,4-benzodiazepinone (CHEBI:35500) |
| Incoming Relation(s) |
| (S)-cyclopeptine (CHEBI:71333) is a cyclopeptine (CHEBI:71320) |
| IUPAC Name |
|---|
| 3-benzyl-4-methyl-3,4-dihydro-1H-1,4-benzodiazepine-2,5-dione |
| UniProt Name | Source |
|---|---|
| cyclopeptine | UniProt |
| Registry Numbers | Sources |
|---|---|
| Reaxys:755945 | Reaxys |
| Citations |
|---|