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CHEBI:6916 - mexiletine

ChEBI IDCHEBI:6916
ChEBI Namemexiletine
Stars
DefinitionAn aromatic ether which is 2,6-dimethylphenyl ether of 2-aminopropan-1-ol.
Secondary ChEBI IDCHEBI:115958
Last Modified22 February 2017
DownloadsMolfile
FormulaC11H17NO
Net Charge0
Average Mass179.263
Monoisotopic Mass179.13101
SMILESCc1cccc(C)c1OCC(C)N
InChIInChI=1S/C11H17NO/c1-8-5-4-6-9(2)11(8)13-7-10(3)12/h4-6,10H,7,12H2,1-3H3
InChIKeyVLPIATFUUWWMKC-UHFFFAOYSA-N
Wikipedia
Roles Classification
Chemical Role:
Bronsted base  A molecular entity capable of accepting a hydron from a donor (Brønsted acid).
Application:
anti-arrhythmia drug  A drug used for the treatment or prevention of cardiac arrhythmias. Anti-arrhythmia drugs may affect the polarisation-repolarisation phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibres.
ChEBI Ontology
Outgoing Relation(s)
mexiletine (CHEBI:6916) has role anti-arrhythmia drug (CHEBI:38070)
mexiletine (CHEBI:6916) is a aromatic ether (CHEBI:35618)
mexiletine (CHEBI:6916) is a primary amino compound (CHEBI:50994)
Incoming Relation(s)
mexiletine hydrochloride (CHEBI:6917) has part mexiletine (CHEBI:6916)
IUPAC Name 
1-(2,6-dimethylphenoxy)propan-2-amine
INNs  Source
mexiletinumChemIDplus
mexiletineChemIDplus
mexiletinaChemIDplus
Synonyms  Source
MexiletineKEGG COMPOUND
1-methyl-2-(2,6-xylyloxy)ethanamineNIST Chemistry WebBook
1-(2',6'-dimethylphenoxy)-2-aminopropaneNIST Chemistry WebBook
1-(2,6-dimethylphenoxy)-2-propanamineNIST Chemistry WebBook
(±)-1-(2,6-dimethylphenoxy)propan-2-amineChEBI
(2RS)-1-(2,6-dimethylphenoxy)-2-aminopropaneChEBI
Manual XrefsDatabases
C07220KEGG COMPOUND
D08215KEGG DRUG
DB00379DrugBank
FR1551055Patent
US3954872Patent
MexiletineWikipedia
HMDB0014523HMDB
LSM-1700LINCS
1794DrugCentral
Registry NumbersSources
Reaxys:2092205Reaxys
CAS:31828-71-4KEGG COMPOUND
CAS:31828-71-4ChemIDplus
CAS:31828-71-4NIST Chemistry WebBook
Citations