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CHEBI:6820 - methapyrilene

ChEBI IDCHEBI:6820
ChEBI Namemethapyrilene
Stars
DefinitionA member of the class of ethylenediamine derivatives that is ethylenediamine in which one of the nitrogens is substituted by two methyl groups, and the other nitrogen is substituted by a 2-pyridyl group and a (2-thienyl)methyl group.
Last Modified22 February 2017
DownloadsMolfile
FormulaC14H19N3S
Net Charge0
Average Mass261.394
Monoisotopic Mass261.12997
SMILESCN(C)CCN(Cc1cccs1)c1ccccn1
InChIInChI=1S/C14H19N3S/c1-16(2)9-10-17(12-13-6-5-11-18-13)14-7-3-4-8-15-14/h3-8,11H,9-10,12H2,1-2H3
InChIKeyHNJJXZKZRAWDPF-UHFFFAOYSA-N
Wikipedia
Roles Classification
Chemical Role:
Bronsted base  A molecular entity capable of accepting a hydron from a donor (Brønsted acid).
Biological Roles:
H1-receptor antagonist  H1-receptor antagonists are the drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine.
carcinogenic agent  A role played by a chemical compound which is known to induce a process of carcinogenesis by corrupting normal cellular pathways, leading to the acquistion of tumoral capabilities.
Applications:
anti-allergic agent  A drug used to treat allergic reactions.
sedative  A central nervous system depressant used to induce drowsiness or sleep or to reduce psychological excitement or anxiety.
H1-receptor antagonist  H1-receptor antagonists are the drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine.
ChEBI Ontology
Outgoing Relation(s)
methapyrilene (CHEBI:6820) has role anti-allergic agent (CHEBI:50857)
methapyrilene (CHEBI:6820) has role carcinogenic agent (CHEBI:50903)
methapyrilene (CHEBI:6820) has role H1-receptor antagonist (CHEBI:37955)
methapyrilene (CHEBI:6820) has role sedative (CHEBI:35717)
methapyrilene (CHEBI:6820) is a ethylenediamine derivative (CHEBI:31577)
Incoming Relation(s)
methapyrilene hydrochloride (CHEBI:38213) has functional parent methapyrilene (CHEBI:6820)
IUPAC Name 
N,N-dimethyl-N'-pyridin-2-yl-N'-[(thiophen-2-yl)methyl]ethane-1,2-diamine
Synonyms  Source
MethapyrileneKEGG COMPOUND
2-[[2-(dimethylamino)ethyl]-2-thenylamino]pyridineNIST Chemistry WebBook
HistadylNIST Chemistry WebBook
LullaminNIST Chemistry WebBook
N,N-dimethyl-N'-pyrid-2-yl-N'-2-thenylethylenediamineChemIDplus
N-(α-pyridyl)-N-(α-thenyl)-N',N'-dimethylethylenediamineNIST Chemistry WebBook
Brand Names  Source
ThionylanDrugBank
LullaminDrugBank
PyrathynDrugBank
PyrinistolDrugBank
Rest-onDrugBank
RestrylDrugBank
Manual XrefsDatabases
C11114KEGG COMPOUND
DB04819DrugBank
US2581868Patent
MethapyrileneWikipedia
LSM-5582LINCS
1738DrugCentral
Registry NumbersSources
Reaxys:220729Reaxys
CAS:91-80-5KEGG COMPOUND
CAS:91-80-5NIST Chemistry WebBook
CAS:91-80-5ChemIDplus
Citations