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CHEBI:6781 - mesoridazine besylate

ChEBI IDCHEBI:6781
ChEBI Namemesoridazine besylate
Stars
DefinitionThe benzenesulfonate salt of mesoridazine prepared using equimolar amounts of mesoridazine and benzenesulfonic acid.
Last Modified10 July 2012
DownloadsMolfile
FormulaC21H26N2OS2.C6H6O3S
Net Charge0
Average Mass544.764
Monoisotopic Mass544.15242
SMILESCN1CCCCC1CCN1c2ccccc2Sc2ccc(S(C)=O)cc21.O=S(=O)(O)c1ccccc1
InChIInChI=1S/C21H26N2OS2.C6H6O3S/c1-22-13-6-5-7-16(22)12-14-23-18-8-3-4-9-20(18)25-21-11-10-17(26(2)24)15-19(21)23;7-10(8,9)6-4-2-1-3-5-6/h3-4,8-11,15-16H,5-7,12-14H2,1-2H3;1-5H,(H,7,8,9)
InChIKeyCRJHBCPQHRVYBS-UHFFFAOYSA-N
Roles Classification
Biological Role:
dopaminergic antagonist  A drug that binds to but does not activate dopamine receptors, thereby blocking the actions of dopamine or exogenous agonists.
Applications:
first generation antipsychotic  Antipsychotic drugs which can have different modes of action but which tend to be more likely than second generation antipsychotics to cause extrapyramidal motor control disabilities such as body rigidity or Parkinson's disease-type movements; such body movements can become permanent even after treatment has ceased.
dopaminergic antagonist  A drug that binds to but does not activate dopamine receptors, thereby blocking the actions of dopamine or exogenous agonists.
ChEBI Ontology
Outgoing Relation(s)
mesoridazine besylate (CHEBI:6781) has part mesoridazine (CHEBI:6780)
mesoridazine besylate (CHEBI:6781) has role dopaminergic antagonist (CHEBI:48561)
mesoridazine besylate (CHEBI:6781) has role first generation antipsychotic (CHEBI:65190)
mesoridazine besylate (CHEBI:6781) is a organosulfonate salt (CHEBI:64382)
IUPAC Name 
10-[2-(1-methylpiperidin-2-yl)ethyl]-2-(methylsulfinyl)-10H-phenothiazine benzenesulfonate
Synonyms  Source
mesoridazine benzenesulfonateChemIDplus
(±)-10-(2-(1-methyl-2-piperidyl)ethyl)-2-(methylsulfinyl)phenothiazine monobenzenesulfonateChemIDplus
10-(2-(1-methyl-2-piperidyl)ethyl)-2-(methylsulfinyl)phenothiazine monobenzenesulfonateChemIDplus
mesoridazine monobenzenesulfonateChEBI
NC 123ChemIDplus
thioridazine-2-sulfoxide besylateChEBI
Brand Names  Source
SerentilKEGG DRUG
LidanarChEBI
SerentilChEBI
LidanilChEBI
Manual XrefsDatabases
D00795KEGG DRUG
DB00933DrugBank
Registry NumbersSources
Reaxys:4121451Reaxys
CAS:32672-69-8KEGG DRUG
CAS:32672-69-8ChemIDplus