CHEBI:6741 - meloxicam

ChEBI IDCHEBI:6741
ChEBI Namemeloxicam
Stars
DefinitionA benzothiazine that is piroxicam in which the pyridin-2-yl group is replaced by a 5-methyl-1,3-thiazol-2-yl group. A non-steroidal anti-inflammatory drug and selective inhibitor of COX-2, it is used particularly for the management of rheumatoid arthritis.
Last Modified19 June 2017
DownloadsMolfile
FormulaC14H13N3O4S2
Net Charge0
Average Mass351.409
Monoisotopic Mass351.03475
SMILESCc1cnc(NC(=O)C2=C(O)c3ccccc3S(=O)(=O)N2C)s1
InChIInChI=1S/C14H13N3O4S2/c1-8-7-15-14(22-8)16-13(19)11-12(18)9-5-3-4-6-10(9)23(20,21)17(11)2/h3-7,18H,1-2H3,(H,15,16,19)
InChIKeyZRVUJXDFFKFLMG-UHFFFAOYSA-N
Roles Classification
Biological Roles:
analgesic  An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms.
cyclooxygenase 2 inhibitor  A cyclooxygenase inhibitor that interferes with the action of cyclooxygenase 2.
human metabolite  Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens).
Applications:
analgesic  An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms.
non-steroidal anti-inflammatory drug  An anti-inflammatory drug that is not a steroid. In addition to anti-inflammatory actions, non-steroidal anti-inflammatory drugs have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins.
antirheumatic drug  A drug used to treat rheumatoid arthritis.
ChEBI Ontology
Outgoing Relation(s)
meloxicam (CHEBI:6741) has role analgesic (CHEBI:35480)
meloxicam (CHEBI:6741) has role antirheumatic drug (CHEBI:35842)
meloxicam (CHEBI:6741) has role cyclooxygenase 2 inhibitor (CHEBI:50629)
meloxicam (CHEBI:6741) has role non-steroidal anti-inflammatory drug (CHEBI:35475)
meloxicam (CHEBI:6741) is a 1,3-thiazoles (CHEBI:38418)
meloxicam (CHEBI:6741) is a benzothiazine (CHEBI:46899)
meloxicam (CHEBI:6741) is a monocarboxylic acid amide (CHEBI:29347)
IUPAC Name 
4-hydroxy-2-methyl-N-(5-methyl-1,3-thiazol-2-yl)-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide
INNs  Source
meloxicamWHO MedNet
meloxicamWHO MedNet
méloxicamWHO MedNet
meloxicamumWHO MedNet
Synonym  Source
UNII-VG2QF83CGLChemIDplus
Brand Name  Source
MobicKEGG DRUG
Manual XrefsDatabases
1676DrugCentral
1751VSDB
C08169KEGG COMPOUND
D00969KEGG DRUG
DB00814DrugBank
DE2756113Patent
HMDB0014952HMDB
US4233299Patent
Registry NumbersSources
Reaxys:5886369Reaxys
CAS:71125-38-7KEGG COMPOUND
Citations