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CHEBI:6601 - lycorine
| Formula | C16H17NO4 |
| Net Charge | 0 |
| Average Mass | 287.315 |
| Monoisotopic Mass | 287.11576 |
| SMILES | [H][C@@]12C3=C[C@H](O)[C@@H](O)[C@@]1([H])c1cc4c(cc1CN2CC3)OCO4 |
| InChI | InChI=1S/C16H17NO4/c18-11-3-8-1-2-17-6-9-4-12-13(21-7-20-12)5-10(9)14(15(8)17)16(11)19/h3-5,11,14-16,18-19H,1-2,6-7H2/t11-,14-,15+,16+/m0/s1 |
| InChIKey | XGVJWXAYKUHDOO-DANNLKNASA-N |
| Species of Metabolite | Component | Source | Comments |
|---|---|---|---|
| Crinum asiaticum var. sinicum (ncbitaxon:223245) | |||
| leaf (BTO:0000713) | PubMed (21314165) | 95% ethanolic extract of dried, powdered leaves | |
| bulb (BTO:0000159) | PubMed (21314165) | 95% ethanolic extract of dried, powdered leaves |
| Roles Classification |
|---|
| Biological Roles: | antimalarial A drug used in the treatment of malaria. Antimalarials are usually classified on the basis of their action against Plasmodia at different stages in their life cycle in the human. protein synthesis inhibitor A compound, usually an anti-bacterial agent or a toxin, which inhibits the synthesis of a protein. plant metabolite Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms. anticoronaviral agent Any antiviral agent which inhibits the activity of coronaviruses. metabolite Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites. |
| Application: | antimalarial A drug used in the treatment of malaria. Antimalarials are usually classified on the basis of their action against Plasmodia at different stages in their life cycle in the human. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| lycorine (CHEBI:6601) has parent hydride galanthan (CHEBI:35646) |
| lycorine (CHEBI:6601) has role anticoronaviral agent (CHEBI:149553) |
| lycorine (CHEBI:6601) has role antimalarial (CHEBI:38068) |
| lycorine (CHEBI:6601) has role plant metabolite (CHEBI:76924) |
| lycorine (CHEBI:6601) has role protein synthesis inhibitor (CHEBI:48001) |
| lycorine (CHEBI:6601) is a indolizidine alkaloid (CHEBI:38511) |
| IUPAC Name |
|---|
| 9,10-(methylenedioxy)-3,12-didehydrogalanthan-1α,2β-diol |
| Synonyms | Source |
|---|---|
| Amarylline | ChemIDplus |
| Galanthidine | ChemIDplus |
| Licorine | ChemIDplus |
| (−)-lycorine | ChEBI |
| Lycorine | KEGG COMPOUND |
| Narcissine | ChemIDplus |
| Citations |
|---|