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CHEBI:65493 - bidebiline D

ChEBI IDCHEBI:65493
ChEBI Namebidebiline D
Stars
DefinitionAn isoquinoline alkaloid that is a dimer of 10-methoxydehydroanonaine. Isolated from the roots of Polyalthia debilis, it exhibits moderate antimalarial activity by inhibiting the growth of the malarial parasite Plasmodium falciparum.
Last Modified21 November 2012
DownloadsMolfile
FormulaC36H28N2O6
Net Charge0
Average Mass584.628
Monoisotopic Mass584.19474
SMILESCOc1ccc2c(-c3c4c5c(cc6c(c5c5cc(OC)ccc35)OCO6)CCN4)c3c4c(cc5c(c4c2c1)OCO5)CCN3
InChIInChI=1S/C36H28N2O6/c1-39-19-3-5-21-23(13-19)31-27-17(11-25-35(31)43-15-41-25)7-9-37-33(27)29(21)30-22-6-4-20(40-2)14-24(22)32-28-18(8-10-38-34(28)30)12-26-36(32)44-16-42-26/h3-6,11-14,37-38H,7-10,15-16H2,1-2H3
InChIKeyHXKKJKCNOAUCEJ-UHFFFAOYSA-N
Species of MetaboliteComponentSourceComments
Polyalthia debilis (ncbitaxon:235800) root (BTO:0001188) PubMed (12762793)
Roles Classification
Biological Roles:
antimalarial  A drug used in the treatment of malaria. Antimalarials are usually classified on the basis of their action against Plasmodia at different stages in their life cycle in the human.
metabolite  Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
metabolite  Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
Application:
antimalarial  A drug used in the treatment of malaria. Antimalarials are usually classified on the basis of their action against Plasmodia at different stages in their life cycle in the human.
ChEBI Ontology
Outgoing Relation(s)
bidebiline D (CHEBI:65493) has functional parent (−)-annonaine (CHEBI:76)
bidebiline D (CHEBI:65493) has role antimalarial (CHEBI:38068)
bidebiline D (CHEBI:65493) has role metabolite (CHEBI:25212)
bidebiline D (CHEBI:65493) is a aromatic ether (CHEBI:35618)
bidebiline D (CHEBI:65493) is a biaryl (CHEBI:64459)
bidebiline D (CHEBI:65493) is a isoquinoline alkaloid (CHEBI:24921)
bidebiline D (CHEBI:65493) is a isoquinolines (CHEBI:24922)
bidebiline D (CHEBI:65493) is a oxacycle (CHEBI:38104)
IUPAC Name 
11,11'-dimethoxy-6,6',7,7'-tetrahydro-5H,5'H-8,8'-bi[1,3]benzodioxolo[6,5,4-de]benzo[g]quinoline
Synonym  Source
bis-7,7'-dehydro-10,10'-dimethoxyanonaineChEBI
Registry NumbersSources
Reaxys:9682777Reaxys
Citations