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CHEBI:65492 - bidebiline C

ChEBI IDCHEBI:65492
ChEBI Namebidebiline C
Stars
DefinitionAn isoquinoline alkaloid that is a dimer of 8-methoxydehydroanonaine. Isolated from the roots of Polyalthia debilis, it exhibits moderate antimalarial activity by inhibiting the growth of the malarial parasite Plasmodium falciparum.
Last Modified3 August 2016
DownloadsMolfile
FormulaC36H28N2O6
Net Charge0
Average Mass584.628
Monoisotopic Mass584.19474
SMILESCOc1cccc2c1c(-c1c3c4c(cc5c(c4c4cccc(OC)c14)OCO5)CCN3)c1c3c(cc4c(c32)OCO4)CCN1
InChIInChI=1S/C36H28N2O6/c1-39-21-7-3-5-19-27(21)31(33-25-17(9-11-37-33)13-23-35(29(19)25)43-15-41-23)32-28-20(6-4-8-22(28)40-2)30-26-18(10-12-38-34(26)32)14-24-36(30)44-16-42-24/h3-8,13-14,37-38H,9-12,15-16H2,1-2H3
InChIKeyOJNKDUUHVWZPHM-UHFFFAOYSA-N
Species of MetaboliteComponentSourceComments
Polyalthia debilis (ncbitaxon:235800) root (BTO:0001188) PubMed (12762793)
Roles Classification
Biological Roles:
antimalarial  A drug used in the treatment of malaria. Antimalarials are usually classified on the basis of their action against Plasmodia at different stages in their life cycle in the human.
metabolite  Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
metabolite  Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
Application:
antimalarial  A drug used in the treatment of malaria. Antimalarials are usually classified on the basis of their action against Plasmodia at different stages in their life cycle in the human.
ChEBI Ontology
Outgoing Relation(s)
bidebiline C (CHEBI:65492) has functional parent (−)-annonaine (CHEBI:76)
bidebiline C (CHEBI:65492) has role antimalarial (CHEBI:38068)
bidebiline C (CHEBI:65492) has role metabolite (CHEBI:25212)
bidebiline C (CHEBI:65492) is a aromatic ether (CHEBI:35618)
bidebiline C (CHEBI:65492) is a biaryl (CHEBI:64459)
bidebiline C (CHEBI:65492) is a isoquinoline alkaloid (CHEBI:24921)
bidebiline C (CHEBI:65492) is a isoquinolines (CHEBI:24922)
bidebiline C (CHEBI:65492) is a oxacycle (CHEBI:38104)
bidebiline C (CHEBI:65492) is a ring assembly (CHEBI:36820)
IUPAC Name 
9,9'-dimethoxy-6,6',7,7'-tetrahydro-5H,5'H-8,8'-bi[1,3]benzodioxolo[6,5,4-de]benzo[g]quinoline
Synonym  Source
bis-7,7'-dehydro-8,8'-dimethoxyanonaineChEBI
Registry NumbersSources
Reaxys:9683084Reaxys
Citations