EMBL-EBI | Chemical Biology | ChEBI

Example searches: iron*, InChI=1S/CH4O/c1-2/h2H,1H3, caffeine | Advanced Search

CHEBI:6518 - lomefloxacin hydrochloride

ChEBI IDCHEBI:6518
ChEBI Namelomefloxacin hydrochloride
Stars
DefinitionThe hydrochloride salt of lomefloxacin. It is administered by mouth to treat bacterial infections including bronchitis and urinary tract infections. It is also used topically as eye drops for the treatment of bacterial conjunctivitis, and as ear drops for the treatment of otitis externa and otitis media.
Last Modified16 November 2010
DownloadsMolfile
FormulaC17H19F2N3O3.HCl
Net Charge0
Average Mass387.814
Monoisotopic Mass387.11613
SMILESCCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNC(C)C3)c(F)c21.Cl
InChIInChI=1S/C17H19F2N3O3.ClH/c1-3-21-8-11(17(24)25)16(23)10-6-12(18)15(13(19)14(10)21)22-5-4-20-9(2)7-22;/h6,8-9,20H,3-5,7H2,1-2H3,(H,24,25);1H
InChIKeyKXEBLAPZMOQCKO-UHFFFAOYSA-N
Roles Classification
Biological Roles:
antimicrobial agent  A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans.
antitubercular agent  A substance that kills or slows the growth of Mycobacterium tuberculosis and is used in the treatment of tuberculosis.
Applications:
photosensitizing agent  A chemical compound that can be excited by light of a specific wavelength and subsequently transfer energy to a chosen reactant. This is commonly molecular oxygen within a cancer tissue, which is converted to (highly rective) singlet state oxygen. This rapidly reacts with any nearby biomolecules, ultimately killing the cancer cells.
antitubercular agent  A substance that kills or slows the growth of Mycobacterium tuberculosis and is used in the treatment of tuberculosis.
ChEBI Ontology
Outgoing Relation(s)
lomefloxacin hydrochloride (CHEBI:6518) has part lomefloxacin (CHEBI:116278)
lomefloxacin hydrochloride (CHEBI:6518) has role antimicrobial agent (CHEBI:33281)
lomefloxacin hydrochloride (CHEBI:6518) has role antitubercular agent (CHEBI:33231)
lomefloxacin hydrochloride (CHEBI:6518) has role photosensitizing agent (CHEBI:47868)
lomefloxacin hydrochloride (CHEBI:6518) is a hydrochloride (CHEBI:36807)
IUPAC Name 
1-ethyl-6,8-difluoro-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride
Synonyms  Source
lomefloxacin HClChemIDplus
(±)-1-ethyl-6,8-difluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid monohydrochlorideChemIDplus
Manual XrefsDatabases
C08053KEGG COMPOUND
D00873KEGG DRUG
DB00978DrugBank
1901VSDB
Registry NumbersSources
Reaxys:7506829Reaxys
CAS:98079-52-8KEGG COMPOUND
CAS:98079-52-8ChemIDplus