CHEBI:6456 - lidocaine

ChEBI IDCHEBI:6456
ChEBI Namelidocaine
Stars
DefinitionThe monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.
Last Modified22 February 2017
DownloadsMolfile
FormulaC14H22N2O
Net Charge0
Average Mass234.343
Monoisotopic Mass234.17321
SMILESCCN(CC)CC(=O)Nc1c(C)cccc1C
InChIInChI=1S/C14H22N2O/c1-5-16(6-2)10-13(17)15-14-11(3)8-7-9-12(14)4/h7-9H,5-6,10H2,1-4H3,(H,15,17)
InChIKeyNNJVILVZKWQKPM-UHFFFAOYSA-N
Wikipedia
Roles Classification
Chemical Roles:
environmental contaminant  Any minor or unwanted substance introduced into the environment that can have undesired effects.
Bronsted base  A molecular entity capable of accepting a hydron from a donor (Brønsted acid).
Biological Roles:
drug allergen  Any drug which causes the onset of an allergic reaction.
xenobiotic  A xenobiotic (Greek, xenos "foreign"; bios "life") is a compound that is foreign to a living organism. Principal xenobiotics include: drugs, carcinogens and various compounds that have been introduced into the environment by artificial means.
Applications:
local anaesthetic  Any member of a group of drugs that reversibly inhibit the propagation of signals along nerves. Wide variations in potency, stability, toxicity, water-solubility and duration of action determine the route used for administration, e.g. topical, intravenous, epidural or spinal block.
drug allergen  Any drug which causes the onset of an allergic reaction.
anti-arrhythmia drug  A drug used for the treatment or prevention of cardiac arrhythmias. Anti-arrhythmia drugs may affect the polarisation-repolarisation phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibres.
ChEBI Ontology
Outgoing Relation(s)
lidocaine (CHEBI:6456) has functional parent glycinamide (CHEBI:42843)
lidocaine (CHEBI:6456) has role anti-arrhythmia drug (CHEBI:38070)
lidocaine (CHEBI:6456) has role drug allergen (CHEBI:88188)
lidocaine (CHEBI:6456) has role environmental contaminant (CHEBI:78298)
lidocaine (CHEBI:6456) has role local anaesthetic (CHEBI:36333)
lidocaine (CHEBI:6456) has role xenobiotic (CHEBI:35703)
lidocaine (CHEBI:6456) is a benzenes (CHEBI:22712)
lidocaine (CHEBI:6456) is a monocarboxylic acid amide (CHEBI:29347)
lidocaine (CHEBI:6456) is a tertiary amino compound (CHEBI:50996)
Incoming Relation(s)
lidocaine hydrochloride (CHEBI:50512) has part lidocaine (CHEBI:6456)
IUPAC Name 
N-(2,6-dimethylphenyl)-N2,N2-diethylglycinamide
Synonyms  Source
2-(Diethylamino)-2',6'-acetoxylidideChemIDplus
2-(Diethylamino)-N-(2,6-dimethylphenyl)acetamideChemIDplus
LidocaineKEGG DRUG
α-diethylamino-2,6-dimethylacetanilideNIST Chemistry WebBook
Brand Name  Source
LidodermDrugBank
Manual XrefsDatabases
C07073KEGG COMPOUND
D00358KEGG DRUG
DB00281DrugBank
US2441498Patent
GB706409Patent
GB758224Patent
LidocaineWikipedia
HMDB0014426HMDB
LSM-3165LINCS
1579DrugCentral
1903VSDB
Registry NumbersSources
Reaxys:2215784Reaxys
CAS:137-58-6ChemIDplus
CAS:137-58-6NIST Chemistry WebBook
Citations