CHEBI:6456 - lidocaine

ChEBI IDCHEBI:6456
ChEBI Namelidocaine
Stars
DefinitionThe monocarboxylic acid amide resulting from the formal condensation of N,N-diethylglycine with 2,6-dimethylaniline.
Last Modified22 February 2017
DownloadsMolfile
FormulaC14H22N2O
Net Charge0
Average Mass234.343
Monoisotopic Mass234.17321
SMILESCCN(CC)CC(=O)Nc1c(C)cccc1C
InChIInChI=1S/C14H22N2O/c1-5-16(6-2)10-13(17)15-14-11(3)8-7-9-12(14)4/h7-9H,5-6,10H2,1-4H3,(H,15,17)
InChIKeyNNJVILVZKWQKPM-UHFFFAOYSA-N
Wikipedia
Roles Classification
Chemical Roles:
environmental contaminant  Any minor or unwanted substance introduced into the environment that can have undesired effects.
Bronsted base  A molecular entity capable of accepting a hydron from a donor (Brønsted acid).
Biological Roles:
drug allergen  Any drug which causes the onset of an allergic reaction.
xenobiotic  A xenobiotic (Greek, xenos "foreign"; bios "life") is a compound that is foreign to a living organism. Principal xenobiotics include: drugs, carcinogens and various compounds that have been introduced into the environment by artificial means.
analgesic  An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms.
anti-obesity agent  Any substance which is used to reduce or control weight.
antiviral agent  A substance that destroys or inhibits replication of viruses.
Applications:
antispasmodic drug  A drug that suppresses spasms. These are usually caused by smooth muscle contraction, especially in tubular organs. The effect is to prevent spasms of the stomach, intestine or urinary bladder.
anti-inflammatory agent  Any compound that has anti-inflammatory effects.
drug allergen  Any drug which causes the onset of an allergic reaction.
antihypertensive agent  Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism.
local anaesthetic  Any member of a group of drugs that reversibly inhibit the propagation of signals along nerves. Wide variations in potency, stability, toxicity, water-solubility and duration of action determine the route used for administration, e.g. topical, intravenous, epidural or spinal block.
antitussive  An agent that suppresses cough. Antitussives have a central or a peripheral action on the cough reflex, or a combination of both. Compare with expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing, and mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration.
bone density conservation agent  An agent that inhibits bone resorption and/or favor bone mineralization and bone regeneration. Used to heal bone fractures and to treat bone diseases such as osteopenia and osteoporosis.
anti-arrhythmia drug  A drug used for the treatment or prevention of cardiac arrhythmias. Anti-arrhythmia drugs may affect the polarisation-repolarisation phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibres.
gastrointestinal drug  A drug used for its effects on the gastrointestinal system, e.g. controlling gastric acidity, regulating gastrointestinal motility and water flow, and improving digestion.
anxiolytic drug  Anxiolytic drugs are agents that alleviate anxiety, tension, and anxiety disorders, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions.
antiinfective agent  A substance used in the prophylaxis or therapy of infectious diseases.
analgesic  An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms.
vulnerary  A drug used in treating and healing of wounds.
cardiovascular drug  A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume.
antineoplastic agent  A substance that inhibits or prevents the proliferation of neoplasms.
ChEBI Ontology
Outgoing Relation(s)
lidocaine (CHEBI:6456) has functional parent glycinamide (CHEBI:42843)
lidocaine (CHEBI:6456) has role analgesic (CHEBI:35480)
lidocaine (CHEBI:6456) has role anti-arrhythmia drug (CHEBI:38070)
lidocaine (CHEBI:6456) has role anti-inflammatory agent (CHEBI:67079)
lidocaine (CHEBI:6456) has role anti-obesity agent (CHEBI:74518)
lidocaine (CHEBI:6456) has role antihypertensive agent (CHEBI:35674)
lidocaine (CHEBI:6456) has role antiinfective agent (CHEBI:35441)
lidocaine (CHEBI:6456) has role antineoplastic agent (CHEBI:35610)
lidocaine (CHEBI:6456) has role antispasmodic drug (CHEBI:53784)
lidocaine (CHEBI:6456) has role antitussive (CHEBI:51177)
lidocaine (CHEBI:6456) has role antiviral agent (CHEBI:22587)
lidocaine (CHEBI:6456) has role anxiolytic drug (CHEBI:35474)
lidocaine (CHEBI:6456) has role bone density conservation agent (CHEBI:50646)
lidocaine (CHEBI:6456) has role cardiovascular drug (CHEBI:35554)
lidocaine (CHEBI:6456) has role drug allergen (CHEBI:88188)
lidocaine (CHEBI:6456) has role environmental contaminant (CHEBI:78298)
lidocaine (CHEBI:6456) has role gastrointestinal drug (CHEBI:55324)
lidocaine (CHEBI:6456) has role local anaesthetic (CHEBI:36333)
lidocaine (CHEBI:6456) has role vulnerary (CHEBI:73336)
lidocaine (CHEBI:6456) has role xenobiotic (CHEBI:35703)
lidocaine (CHEBI:6456) is a benzenes (CHEBI:22712)
lidocaine (CHEBI:6456) is a monocarboxylic acid amide (CHEBI:29347)
lidocaine (CHEBI:6456) is a tertiary amino compound (CHEBI:50996)
Incoming Relation(s)
lidocaine hydrochloride (CHEBI:50512) has part lidocaine (CHEBI:6456)
IUPAC Name 
N-(2,6-dimethylphenyl)-N2,N2-diethylglycinamide
INN  Source
lidocainaWHO MedNet
Synonyms  Source
2-(Diethylamino)-2',6'-acetoxylidideChemIDplus
2-(Diethylamino)-N-(2,6-dimethylphenyl)acetamideChemIDplus
ALGRX 3268ChEMBL
ALGRX-3268ChEMBL
EmbolexChEMBL
IontocaineChEMBL
Brand Names  Source
AlphacaineChEMBL
DentipatchChEMBL
Lidocaine component of emlaChEMBL
Lidocaine component of fortacinChEMBL
Lidocaine component of lanabioticChEMBL
Lidocaine component of oraqixChEMBL
Manual XrefsDatabases
1579DrugCentral
1903VSDB
C07073KEGG COMPOUND
D00358KEGG DRUG
DB00281DrugBank
GB706409Patent
GB758224Patent
HMDB0014426HMDB
LidocaineWikipedia
LSM-3165LINCS
US2441498Patent
Registry NumbersSources
Reaxys:2215784Reaxys
CAS:137-58-6ChemIDplus
CAS:137-58-6NIST Chemistry WebBook
Citations