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CHEBI:64358 - rivastigmine tartrate

Default Structure
ChEBI IDCHEBI:64358
ChEBI Namerivastigmine tartrate
Stars
DefinitionA tartrate salt obtained by reaction of rivastigmine with one equivalent of (R,R)-tartaric acid. A reversible cholinesterase inhibitor.
Last Modified11 April 2012
DownloadsMolfile
FormulaC14H22N2O2.C4H6O6
Net Charge0
Average Mass400.428
Monoisotopic Mass400.18457
SMILESCCN(C)C(=O)Oc1cccc([C@H](C)N(C)C)c1.O=C(O)[C@H](O)[C@@H](O)C(=O)O
InChIInChI=1S/C14H22N2O2.C4H6O6/c1-6-16(5)14(17)18-13-9-7-8-12(10-13)11(2)15(3)4;5-1(3(7)8)2(6)4(9)10/h7-11H,6H2,1-5H3;1-2,5-6H,(H,7,8)(H,9,10)/t11-;1-,2-/m01/s1
InChIKeyGWHQHAUAXRMMOT-MBANBULQSA-N
Roles Classification
Biological Roles:
cholinergic drug  Any drug used for its actions on cholinergic systems. Included here are agonists and antagonists, drugs that affect the life cycle of acetylcholine, and drugs that affect the survival of cholinergic neurons.
EC 3.1.1.8 (cholinesterase) inhibitor  An EC 3.1.1.* (carboxylic ester hydrolase) inhibitor that interferes with the action of cholinesterase (EC 3.1.1.8).
Applications:
cholinergic drug  Any drug used for its actions on cholinergic systems. Included here are agonists and antagonists, drugs that affect the life cycle of acetylcholine, and drugs that affect the survival of cholinergic neurons.
vasoconstrictor agent  Drug used to cause constriction of the blood vessels.
antiparkinson drug  A drug used in the treatment of Parkinson's disease.
neuroprotective agent  Any compound that can be used for the treatment of neurodegenerative disorders.
ChEBI Ontology
Outgoing Relation(s)
rivastigmine tartrate (CHEBI:64358) has part rivastigmine(1+) (CHEBI:64363)
rivastigmine tartrate (CHEBI:64358) has role antiparkinson drug (CHEBI:48407)
rivastigmine tartrate (CHEBI:64358) has role cholinergic drug (CHEBI:38323)
rivastigmine tartrate (CHEBI:64358) has role EC 3.1.1.8 (cholinesterase) inhibitor (CHEBI:37733)
rivastigmine tartrate (CHEBI:64358) has role neuroprotective agent (CHEBI:63726)
rivastigmine tartrate (CHEBI:64358) has role vasoconstrictor agent (CHEBI:50514)
rivastigmine tartrate (CHEBI:64358) is a tartrate salt (CHEBI:50562)
IUPAC Name 
3-[(1S)-1-(dimethylamino)ethyl]phenyl ethyl(methyl)carbamate (2R,3R)-2,3-dihydroxybutanedioate
Synonyms  Source
(1S)-1-(3-{[ethyl(methyl)carbamoyl]oxy}phenyl)-N,N-dimethylethanaminium (2R,3R)-3-carboxy-2,3-dihydroxypropanoateIUPAC
ENA 713ChEMBL
Rivastigmine actavisChEMBL
Rivastigmine bitartrateChEMBL
rivastigmine hydrogen tartrateDrugBank
Rivastigmine hydrogentartrateChEMBL
Brand Names  Source
ExelonKEGG DRUG
Exelon tartrateChEMBL
NimvastidChEMBL
Rivastigmine 1 a pharmaChEMBL
Rivastigmine sandozChEMBL
Rivastigmine tevaChEMBL
Manual XrefsDatabases
D02558KEGG DRUG
DB00989DrugBank
EP1980552Patent
EP2233465Patent
US2008255383Patent
US2008306280Patent
Registry NumbersSources
Reaxys:9305032Reaxys
CAS:129101-54-8ChemIDplus
CAS:129101-54-8KEGG DRUG
Citations