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CHEBI:643228 - betaxolol hydrochloride

ChEBI IDCHEBI:643228
ChEBI Namebetaxolol hydrochloride
Stars
DefinitionThe hydrochloride salt of betaxolol.
Secondary ChEBI IDsCHEBI:3083, CHEBI:101332
Last Modified21 April 2010
DownloadsMolfile
FormulaC18H30NO3.Cl
Net Charge0
Average Mass343.895
Monoisotopic Mass343.19142
SMILESCC(C)[NH2+]CC(O)COc1ccc(CCOCC2CC2)cc1.[Cl-]
InChIInChI=1S/C18H29NO3.ClH/c1-14(2)19-11-17(20)13-22-18-7-5-15(6-8-18)9-10-21-12-16-3-4-16;/h5-8,14,16-17,19-20H,3-4,9-13H2,1-2H3;1H
InChIKeyCHDPSNLJFOQTRK-UHFFFAOYSA-N
Roles Classification
Biological Role:
beta-adrenergic antagonist  An agent that binds to but does not activate β-adrenergic receptors thereby blocking the actions of endogenous or exogenous β-adrenergic agonists. β-Adrenergic antagonists are used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches and anxiety.
Applications:
antihypertensive agent  Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism.
beta-adrenergic antagonist  An agent that binds to but does not activate β-adrenergic receptors thereby blocking the actions of endogenous or exogenous β-adrenergic agonists. β-Adrenergic antagonists are used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches and anxiety.
ChEBI Ontology
Outgoing Relation(s)
betaxolol hydrochloride (CHEBI:643228) has part betaxolol (CHEBI:3082)
betaxolol hydrochloride (CHEBI:643228) has role antihypertensive agent (CHEBI:35674)
betaxolol hydrochloride (CHEBI:643228) has role β-adrenergic antagonist (CHEBI:35530)
betaxolol hydrochloride (CHEBI:643228) is a hydrochloride (CHEBI:36807)
Incoming Relation(s)
(R)-betaxolol hydrochloride (CHEBI:59255) is a betaxolol hydrochloride (CHEBI:643228)
(S)-betaxolol hydrochloride (CHEBI:59256) is a betaxolol hydrochloride (CHEBI:643228)
IUPAC Name 
1-{4-[2-(cyclopropylmethoxy)ethyl]phenoxy}-3-(propan-2-ylamino)propan-2-ol hydrochloride
Synonyms  Source
1-[4-(2-Cyclopropylmethoxy-ethyl)-phenoxy]-3-isopropylamino-propan-2-ol; hydrochlorideChEMBL
Betaxolol hydrochlorideChEMBL
3-{4-[2-(cyclopropylmethoxy)ethyl]phenoxy}-2-hydroxy-N-(propan-2-yl)propan-1-aminium chlorideIUPAC
1-(p-(2-(cyclopropylmethoxy)ethyl)phenoxy)-3-(isopropylamino)-2-propanol hydrochlorideChemIDplus
betaxolol HClChemIDplus
1-(isopropylamino)-3-[p-(cyclopropylmethoxyethyl)phenoxy]-2-propanol hydrochlorideChEBI
Manual XrefsDatabases
D00598KEGG DRUG
DB00195DrugBank
Registry NumbersSources
Beilstein:5182512Beilstein
CAS:63659-19-8ChemIDplus