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CHEBI:64144 - 1-[1-(1-benzothiophen-2-yl)cyclohexyl]piperidine maleate

ChEBI IDCHEBI:64144
ChEBI Name1-[1-(1-benzothiophen-2-yl)cyclohexyl]piperidine maleate
Stars
DefinitionA maleate salt obtained by reaction of 1-[1-(1-benzothiophen-2-yl)cyclohexyl]piperidine with one equivalent of maleic acid. A potent dopamine re-uptake inhibitor with a behavioral profile different from that of PCP and similar to that of cocaine.
Last Modified21 September 2021
SubmitterSteve
DownloadsMolfile
FormulaC19H25NS.C4H4O4
Net Charge0
Average Mass415.555
Monoisotopic Mass415.18173
SMILESO=C(O)/C=C\C(=O)O.c1ccc2sc(C3(N4CCCCC4)CCCCC3)cc2c1
InChIInChI=1S/C19H25NS.C4H4O4/c1-5-11-19(12-6-1,20-13-7-2-8-14-20)18-15-16-9-3-4-10-17(16)21-18;5-3(6)1-2-4(7)8/h3-4,9-10,15H,1-2,5-8,11-14H2;1-2H,(H,5,6)(H,7,8)/b;2-1-
InChIKeyAMTYJSWZECGJOO-BTJKTKAUSA-N
Roles Classification
Biological Role:
dopamine uptake inhibitor  A dopaminergic agent that blocks the transport of dopamine into axon terminals or into storage vesicles within terminals. Most of the adrenergic uptake inhibitors also inhibit dopamine uptake.
Application:
dopamine uptake inhibitor  A dopaminergic agent that blocks the transport of dopamine into axon terminals or into storage vesicles within terminals. Most of the adrenergic uptake inhibitors also inhibit dopamine uptake.
ChEBI Ontology
Outgoing Relation(s)
1-[1-(1-benzothiophen-2-yl)cyclohexyl]piperidine maleate (CHEBI:64144) has part 1-[1-(1-benzothiophen-2-yl)cyclohexyl]piperidinium(1+) (CHEBI:64146)
1-[1-(1-benzothiophen-2-yl)cyclohexyl]piperidine maleate (CHEBI:64144) has role dopamine uptake inhibitor (CHEBI:51039)
1-[1-(1-benzothiophen-2-yl)cyclohexyl]piperidine maleate (CHEBI:64144) is a maleate salt (CHEBI:50221)
IUPAC Name 
1-[1-(1-benzothiophen-2-yl)cyclohexyl]piperidine (2Z)-but-2-enedioate
Synonyms  Source
BTCP maleateChEBI
1-[1-(1-benzothiophen-2-yl)cyclohexyl]piperidinium (2Z)-3-carboxyacrylateIUPAC
benocyclidine maleateChEBI
Manual XrefsDatabases
8426776ChemSpider
Registry NumbersSources
CAS:207455-25-2ChEBI