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CHEBI:6367 - lamotrigine
| Formula | C9H7Cl2N5 |
| Net Charge | 0 |
| Average Mass | 256.096 |
| Monoisotopic Mass | 255.00785 |
| SMILES | Nc1nnc(-c2cccc(Cl)c2Cl)c(N)n1 |
| InChI | InChI=1S/C9H7Cl2N5/c10-5-3-1-2-4(6(5)11)7-8(12)14-9(13)16-15-7/h1-3H,(H4,12,13,14,16) |
| InChIKey | PYZRQGJRPPTADH-UHFFFAOYSA-N |
| Wikipedia |
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| Roles Classification |
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| Chemical Roles: | environmental contaminant Any minor or unwanted substance introduced into the environment that can have undesired effects. Bronsted base A molecular entity capable of accepting a hydron from a donor (Brønsted acid). |
| Biological Roles: | immunosuppressive agent An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response. anti-obesity agent Any substance which is used to reduce or control weight. non-narcotic analgesic A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors. calcium channel blocker One of a class of drugs that acts by selective inhibition of calcium influx through cell membranes or on the release and binding of calcium in intracellular pools. EC 3.4.21.26 (prolyl oligopeptidase) inhibitor Any EC 3.4.21.* (serine endopeptidase) inhibitor that interferes with the action of prolyl oligopeptidase (EC 3.4.21.26). excitatory amino acid antagonist Any substance which inhibits the action of receptors for excitatory amino acids. analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. anti-HIV agent An antiviral agent that destroys or inhibits the replication of the human immunodeficiency virus. xenobiotic A xenobiotic (Greek, xenos "foreign"; bios "life") is a compound that is foreign to a living organism. Principal xenobiotics include: drugs, carcinogens and various compounds that have been introduced into the environment by artificial means. |
| Applications: | antimanic drug Antimanic drugs are agents used to treat bipolar disorders or mania associated with other affective disorders. geroprotector Any compound that supports healthy aging, slows the biological aging process, or extends lifespan. immunosuppressive agent An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response. non-narcotic analgesic A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors. anticonvulsant A drug used to prevent seizures or reduce their severity. analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. anxiolytic drug Anxiolytic drugs are agents that alleviate anxiety, tension, and anxiety disorders, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions. antidepressant Antidepressants are mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. antipsychotic agent Antipsychotic drugs are agents that control agitated psychotic behaviour, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| lamotrigine (CHEBI:6367) has role analgesic (CHEBI:35480) |
| lamotrigine (CHEBI:6367) has role anti-HIV agent (CHEBI:64946) |
| lamotrigine (CHEBI:6367) has role anti-obesity agent (CHEBI:74518) |
| lamotrigine (CHEBI:6367) has role anticonvulsant (CHEBI:35623) |
| lamotrigine (CHEBI:6367) has role antidepressant (CHEBI:35469) |
| lamotrigine (CHEBI:6367) has role antimanic drug (CHEBI:35477) |
| lamotrigine (CHEBI:6367) has role antipsychotic agent (CHEBI:35476) |
| lamotrigine (CHEBI:6367) has role anxiolytic drug (CHEBI:35474) |
| lamotrigine (CHEBI:6367) has role calcium channel blocker (CHEBI:38215) |
| lamotrigine (CHEBI:6367) has role EC 3.4.21.26 (prolyl oligopeptidase) inhibitor (CHEBI:76779) |
| lamotrigine (CHEBI:6367) has role environmental contaminant (CHEBI:78298) |
| lamotrigine (CHEBI:6367) has role excitatory amino acid antagonist (CHEBI:60798) |
| lamotrigine (CHEBI:6367) has role geroprotector (CHEBI:176497) |
| lamotrigine (CHEBI:6367) has role immunosuppressive agent (CHEBI:35705) |
| lamotrigine (CHEBI:6367) has role non-narcotic analgesic (CHEBI:35481) |
| lamotrigine (CHEBI:6367) has role xenobiotic (CHEBI:35703) |
| lamotrigine (CHEBI:6367) is a 1,2,4-triazines (CHEBI:39410) |
| lamotrigine (CHEBI:6367) is a dichlorobenzene (CHEBI:23697) |
| lamotrigine (CHEBI:6367) is a primary arylamine (CHEBI:50471) |
| IUPAC Name |
|---|
| 6-(2,3-dichlorophenyl)-1,2,4-triazine-3,5-diamine |
| INNs | Source |
|---|---|
| lamotrigina | ChemIDplus |
| lamotrigine | ChemIDplus |
| lamotriginum | ChemIDplus |
| Synonyms | Source |
|---|---|
| 3,5-diamino-6-(2,3-dichlorophenyl)-1,2,4-triazine | ChemIDplus |
| BW-430C | ChEMBL |
| NSC-759171 | ChEMBL |
| Brand Names | Source |
|---|---|
| Lamictal | KEGG DRUG |
| Lamictal cd | ChEMBL |
| Lamictal odt | ChEMBL |
| Lamictal xr | ChEMBL |
| Manual Xrefs | Databases |
|---|---|
| 1540 | DrugCentral |
| D00354 | KEGG DRUG |
| DB00555 | DrugBank |
| HMDB0014695 | HMDB |
| Lamotrigine | Wikipedia |
| LSM-4104 | LINCS |
| Registry Numbers | Sources |
|---|---|
| Reaxys:7589268 | Reaxys |
| CAS:84057-84-1 | KEGG DRUG |
| CAS:84057-84-1 | ChemIDplus |
| CAS:84057-84-1 | NIST Chemistry WebBook |
| Citations |
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