CHEBI:63614 - olsalazine sodium

ChEBI IDCHEBI:63614
ChEBI Nameolsalazine sodium
Stars
DefinitionAn organic sodium salt that is the disodium salt of 3,3'-azobis(6-hydroxybenzoic acid) (olsalazine). Effective in the treatment of inflammatory bowel disease and ulcerative colitis. Mechanism of action unknown, but appears to be topical
Secondary ChEBI IDCHEBI:7771
Last Modified10 April 2013
DownloadsMolfile
FormulaC14H8N2O6.2Na
Net Charge0
Average Mass346.206
Monoisotopic Mass346.01777
SMILESO=C([O-])c1cc(N=Nc2ccc(O)c(C(=O)[O-])c2)ccc1O.[Na+].[Na+]
InChIInChI=1S/C14H10N2O6.2Na/c17-11-3-1-7(5-9(11)13(19)20)15-16-8-2-4-12(18)10(6-8)14(21)22;;/h1-6,17-18H,(H,19,20)(H,21,22);;/q;2*+1/p-2
InChIKeyZJEFYLVGGFISGT-UHFFFAOYSA-L
Roles Classification
Applications:
prodrug  A compound that, on administration, must undergo chemical conversion by metabolic processes before becoming the pharmacologically active drug for which it is a prodrug.
non-steroidal anti-inflammatory drug  An anti-inflammatory drug that is not a steroid. In addition to anti-inflammatory actions, non-steroidal anti-inflammatory drugs have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins.
ChEBI Ontology
Outgoing Relation(s)
olsalazine sodium (CHEBI:63614) has part olsalazine(2−) (CHEBI:63719)
olsalazine sodium (CHEBI:63614) has role non-steroidal anti-inflammatory drug (CHEBI:35475)
olsalazine sodium (CHEBI:63614) has role prodrug (CHEBI:50266)
olsalazine sodium (CHEBI:63614) is a organic sodium salt (CHEBI:38700)
IUPAC Name 
disodium 3,3'-diazene-1,2-diylbis(6-hydroxybenzoate)
Synonyms  Source
Disodium 5,5'-azodisalicylateChemIDplus
disodium 3,3'-azobis (6-hydroxybenzoate)ChEBI
Manual XrefsDatabases
D00727KEGG DRUG
DB01250DrugBank
Registry NumbersSources
Reaxys:9027885Reaxys
CAS:6054-98-4KEGG DRUG
CAS:6054-98-4ChemIDplus
Citations