EMBL-EBI | Chemical Biology | ChEBI
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| ChEBI ID | CHEBI:63609 |
| ChEBI Name | mefloquine |
| Stars | |
| Definition | A racemate composed of (+)-(11R,2'S)- and (−)-(11S,2'R)-enantiomers of mefloquine. An antimalarial agent which acts as a blood schizonticide; its mechanism of action is unknown. |
| Secondary ChEBI ID | CHEBI:6718 |
| Last Modified | 23 April 2020 |
| Wikipedia |
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| Roles Classification |
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| Biological Roles: | anticoronaviral agent Any antiviral agent which inhibits the activity of coronaviruses. antimalarial A drug used in the treatment of malaria. Antimalarials are usually classified on the basis of their action against Plasmodia at different stages in their life cycle in the human. |
| Application: | antimalarial A drug used in the treatment of malaria. Antimalarials are usually classified on the basis of their action against Plasmodia at different stages in their life cycle in the human. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| mefloquine (CHEBI:63609) has part (+)-(11R,2'S)-erythro-mefloquine (CHEBI:63684) |
| mefloquine (CHEBI:63609) has part (−)-(11S,2'R)-erythro-mefloquine (CHEBI:63687) |
| mefloquine (CHEBI:63609) has role anticoronaviral agent (CHEBI:149553) |
| mefloquine (CHEBI:63609) has role antimalarial (CHEBI:38068) |
| mefloquine (CHEBI:63609) is a racemate (CHEBI:60911) |
| IUPAC Name |
|---|
| rac--(R)-[2,8-bis(trifluoromethyl)quinolin-4-yl][(2S)-piperidin-2-yl]methanol |
| INNs | Source |
|---|---|
| mefloquine | KEGG DRUG |
| mefloquinum | ChemIDplus |
| mefloquina | ChemIDplus |
| Synonyms | Source |
|---|---|
| [DL-erythro-alpha-2-Piperidyl-2,8-bis(trifluoromethyl)]-4-quinolinemethanol | ChemIDplus |
| Racemic mefloquine | ChemIDplus |
| [(R*,S*)-2,8-bis(trifluoromethyl)quinolin-4-yl]-(2-piperidyl)methanol | ChEBI |
| Manual Xrefs | Databases |
|---|---|
| C07633 | KEGG COMPOUND |
| D04895 | KEGG DRUG |
| DB00358 | DrugBank |
| Mefloquine | Wikipedia |
| Registry Numbers | Sources |
|---|---|
| Reaxys:5306591 | Reaxys |
| CAS:53230-10-7 | KEGG COMPOUND |
| CAS:53230-10-7 | ChemIDplus |
| Citations |
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