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CHEBI:63609 - mefloquine
| ChEBI ID | CHEBI:63609 |
| ChEBI Name | mefloquine |
| Stars | |
| Definition | A racemate composed of (+)-(11R,2'S)- and (−)-(11S,2'R)-enantiomers of mefloquine. An antimalarial agent which acts as a blood schizonticide; its mechanism of action is unknown. |
| Secondary ChEBI ID | CHEBI:6718 |
| Last Modified | 23 April 2020 |
| Wikipedia |
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| Roles Classification |
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| Biological Roles: | antiviral agent A substance that destroys or inhibits replication of viruses. antimalarial A drug used in the treatment of malaria. Antimalarials are usually classified on the basis of their action against Plasmodia at different stages in their life cycle in the human. anticoronaviral agent Any antiviral agent which inhibits the activity of coronaviruses. |
| Applications: | antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. antimalarial A drug used in the treatment of malaria. Antimalarials are usually classified on the basis of their action against Plasmodia at different stages in their life cycle in the human. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| mefloquine (CHEBI:63609) has part (+)-(11R,2'S)-erythro-mefloquine (CHEBI:63684) |
| mefloquine (CHEBI:63609) has part (−)-(11S,2'R)-erythro-mefloquine (CHEBI:63687) |
| mefloquine (CHEBI:63609) has role anticoronaviral agent (CHEBI:149553) |
| mefloquine (CHEBI:63609) has role antimalarial (CHEBI:38068) |
| mefloquine (CHEBI:63609) has role antineoplastic agent (CHEBI:35610) |
| mefloquine (CHEBI:63609) has role antiviral agent (CHEBI:22587) |
| mefloquine (CHEBI:63609) is a racemate (CHEBI:60911) |
| IUPAC Name |
|---|
| rac--(R)-[2,8-bis(trifluoromethyl)quinolin-4-yl][(2S)-piperidin-2-yl]methanol |
| INNs | Source |
|---|---|
| mefloquina | ChemIDplus |
| mefloquine | KEGG DRUG |
| mefloquinum | ChemIDplus |
| Synonyms | Source |
|---|---|
| [DL-erythro-alpha-2-Piperidyl-2,8-bis(trifluoromethyl)]-4-quinolinemethanol | ChemIDplus |
| GNF-Pf-5544 | ChEMBL |
| [(R*,S*)-2,8-bis(trifluoromethyl)quinolin-4-yl]-(2-piperidyl)methanol | ChEBI |
| Mefaquin | ChEMBL |
| NSC-758233 | ChEMBL |
| Racemic mefloquine | ChemIDplus |
| Manual Xrefs | Databases |
|---|---|
| C07633 | KEGG COMPOUND |
| D04895 | KEGG DRUG |
| DB00358 | DrugBank |
| Mefloquine | Wikipedia |
| Registry Numbers | Sources |
|---|---|
| Reaxys:5306591 | Reaxys |
| CAS:53230-10-7 | KEGG COMPOUND |
| CAS:53230-10-7 | ChemIDplus |
| Citations |
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