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CHEBI:60792 - methohexital(1−)

ChEBI IDCHEBI:60792
ChEBI Namemethohexital(1−)
Stars
ASCII Namemethohexital(1-)
DefinitionThe anion resulting from the removal of a proton from the N3 position of methohexital.
Last Modified21 August 2023
SubmitterGareth Owen
DownloadsMolfile
FormulaC14H17N2O3
Net Charge-1
Average Mass261.301
Monoisotopic Mass261.12447
SMILESC=CCC1(C(C)C#CCC)C(=O)N=C([O-])N(C)C1=O
InChIInChI=1S/C14H18N2O3/c1-5-7-8-10(3)14(9-6-2)11(17)15-13(19)16(4)12(14)18/h6,10H,2,5,9H2,1,3-4H3,(H,15,17,19)/p-1
InChIKeyNZXKDOXHBHYTKP-UHFFFAOYSA-M
Roles Classification
Biological Role:
GABA modulator  A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
Application:
GABA modulator  A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
ChEBI Ontology
Outgoing Relation(s)
methohexital(1−) (CHEBI:60792) is a barbiturate anion (CHEBI:22691)
methohexital(1−) (CHEBI:60792) is conjugate base of methohexital (CHEBI:102216)
Incoming Relation(s)
methohexital sodium (CHEBI:6834) has part methohexital(1−) (CHEBI:60792)
methohexital (CHEBI:102216) is conjugate acid of methohexital(1−) (CHEBI:60792)
IUPAC Name 
5-(hex-3-yn-2-yl)-1-methyl-4,6-dioxo-5-(prop-2-en-1-yl)-1,4,5,6-tetrahydropyrimidin-2-olate
Synonym  Source
methohexital anionChEBI