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CHEBI:60269 - trisodium phosphonoformate hexahydrate

ChEBI IDCHEBI:60269
ChEBI Nametrisodium phosphonoformate hexahydrate
Stars
DefinitionThe hexahydrate form of trisodium phosphonoformate. It is used as an antiviral agent in the treatment of cytomegalovirus retinitis (CMV retinitis, an inflamation of the retina that can lead to blindness) and as an alternative to ganciclovir for AIDS patients who require concurrent antiretroviral therapy but are unable to tolerate ganciclovir due to haematological toxicity.
Last Modified12 June 2012
SubmitterGareth Owen
DownloadsMolfile
FormulaCO5P.6H2O.3Na
Net Charge0
Average Mass300.040
Monoisotopic Mass299.98103
SMILESO.O.O.O.O.O.O=C([O-])P(=O)([O-])[O-].[Na+].[Na+].[Na+]
InChIInChI=1S/CH3O5P.3Na.6H2O/c2-1(3)7(4,5)6;;;;;;;;;/h(H,2,3)(H2,4,5,6);;;;6*1H2/q;3*+1;;;;;;/p-3
InChIKeyILRVASBWNRYBFD-UHFFFAOYSA-K
Roles Classification
Biological Role:
antiviral drug  A substance used in the prophylaxis or therapy of virus diseases.
Application:
antiviral drug  A substance used in the prophylaxis or therapy of virus diseases.
ChEBI Ontology
Outgoing Relation(s)
trisodium phosphonoformate hexahydrate (CHEBI:60269) has part trisodium phosphonoformate (CHEBI:141644)
trisodium phosphonoformate hexahydrate (CHEBI:60269) has role antiviral drug (CHEBI:36044)
trisodium phosphonoformate hexahydrate (CHEBI:60269) is a hydrate (CHEBI:35505)
trisodium phosphonoformate hexahydrate (CHEBI:60269) is a one-carbon compound (CHEBI:64708)
Synonyms  Source
trisodium phosphonoformate hexahydrateKEGG DRUG
foscarnet sodium hexahydrateKEGG DRUG
Manual XrefsDatabases
D02267KEGG DRUG
DB00529DrugBank
Registry NumbersSources
CAS:34156-56-4KEGG DRUG
CAS:34156-56-4ChemIDplus