EMBL-EBI | Chemical Biology | ChEBI

Example searches: iron*, InChI=1S/CH4O/c1-2/h2H,1H3, caffeine | Advanced Search

CHEBI:141644 - trisodium phosphonoformate

ChEBI IDCHEBI:141644
ChEBI Nametrisodium phosphonoformate
Stars
DefinitionThe trisodium salt of phosphonoformic acid. It is used as an antiviral agent in the treatment of cytomegalovirus retinitis (CMV retinitis, an inflamation of the retina that can lead to blindness) and as an alternative to ganciclovir for AIDS patients who require concurrent antiretroviral therapy but are unable to tolerate ganciclovir due to haematological toxicity.
Secondary ChEBI IDCHEBI:5161
Last Modified6 March 2017
DownloadsMolfile
FormulaCO5P.3Na
Net Charge0
Average Mass191.950
Monoisotopic Mass191.91764
SMILESO=C([O-])P(=O)([O-])[O-].[Na+].[Na+].[Na+]
InChIInChI=1S/CH3O5P.3Na/c2-1(3)7(4,5)6;;;/h(H,2,3)(H2,4,5,6);;;/q;3*+1/p-3
InChIKeyDFHAXXVZCFXGOQ-UHFFFAOYSA-K
Roles Classification
Biological Role:
antiviral drug  A substance used in the prophylaxis or therapy of virus diseases.
Application:
antiviral drug  A substance used in the prophylaxis or therapy of virus diseases.
ChEBI Ontology
Outgoing Relation(s)
trisodium phosphonoformate (CHEBI:141644) has part phosphonatoformate (CHEBI:60268)
trisodium phosphonoformate (CHEBI:141644) has role antiviral drug (CHEBI:36044)
trisodium phosphonoformate (CHEBI:141644) is a one-carbon compound (CHEBI:64708)
trisodium phosphonoformate (CHEBI:141644) is a organic sodium salt (CHEBI:38700)
Incoming Relation(s)
trisodium phosphonoformate hexahydrate (CHEBI:60269) has part trisodium phosphonoformate (CHEBI:141644)
INNs  Source
foscarnet sodiumKEGG DRUG
foscarnet sodiqueChemIDplus
foscarneto sodicoChemIDplus
foscarnetum natricumChemIDplus
Synonyms  Source
trisodium phosphonoformateChEMBL
foscarnet sodiumChEMBL
trisodium dioxidophosphinecarboxylate oxideChEMBL
FOSCARNET SODIUMChEMBL
trisodium carboxyphosphateChemIDplus
trisodium phosphonoformate (anhydrous)ChEBI
Manual XrefsDatabases
D00579KEGG DRUG
DB00529DrugBank
Registry NumbersSources
CAS:63585-09-1KEGG DRUG
CAS:63585-09-1ChemIDplus