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CHEBI:59938 - ciprofloxacin dihydrochloride

ChEBI IDCHEBI:59938
ChEBI Nameciprofloxacin dihydrochloride
Stars
DefinitionThe dihydrochloride salt of ciprofloxacin.
Last Modified2 August 2010
SubmitterGareth Owen
DownloadsMolfile
FormulaC17H18FN3O3.2HCl
Net Charge0
Average Mass404.269
Monoisotopic Mass403.08658
SMILESCl.Cl.O=C(O)c1cn(C2CC2)c2cc(N3CCNCC3)c(F)cc2c1=O
InChIInChI=1S/C17H18FN3O3.2ClH/c18-13-7-11-14(8-15(13)20-5-3-19-4-6-20)21(10-1-2-10)9-12(16(11)22)17(23)24;;/h7-10,19H,1-6H2,(H,23,24);2*1H
InChIKeyPWRKLYZVCZMDTC-UHFFFAOYSA-N
Roles Classification
Biological Roles:
topoisomerase IV inhibitor  A topoisomerase inhibitor that inhibits DNA topoisomerase IV, which catalyses ATP-dependent breakage of both strands of DNA, passage of the unbroken strands through the breaks, and rejoining of the broken strands.
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor  A topoisomerase inhibitor that inhibits DNA topoisomerase (ATP-hydrolysing), EC 5.99.1.3 (also known as topoisomerase II and as DNA gyrase), which catalyses ATP-dependent breakage of both strands of DNA, passage of the unbroken strands through the breaks, and rejoining of the broken strands.
antibacterial drug  A drug used to treat or prevent bacterial infections.
Applications:
antiinfective agent  A substance used in the prophylaxis or therapy of infectious diseases.
antibacterial drug  A drug used to treat or prevent bacterial infections.
ChEBI Ontology
Outgoing Relation(s)
ciprofloxacin dihydrochloride (CHEBI:59938) has part ciprofloxacin hydrochloride (anhydrous) (CHEBI:310388)
ciprofloxacin dihydrochloride (CHEBI:59938) has role antibacterial drug (CHEBI:36047)
ciprofloxacin dihydrochloride (CHEBI:59938) has role antiinfective agent (CHEBI:35441)
ciprofloxacin dihydrochloride (CHEBI:59938) has role EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor (CHEBI:50750)
ciprofloxacin dihydrochloride (CHEBI:59938) has role topoisomerase IV inhibitor (CHEBI:53559)
ciprofloxacin dihydrochloride (CHEBI:59938) is a hydrochloride (CHEBI:36807)
IUPAC Name 
1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid dihydrochloride
Synonym  Source
1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid dihydrochlorideChEBI