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CHEBI:59837 - doxapram hydrochloride (anhydrous)

ChEBI IDCHEBI:59837
ChEBI Namedoxapram hydrochloride (anhydrous)
Stars
DefinitionThe hydrochloride salt of doxapram. A central and respiratory stimulant with a brief duration of action, both doxapram hydrochloride and its hydrate are used as a temporary treatment of acute respiratory failure, particularly when superimposed on chronic obstructive pulmonary disease, and of postoperative respiratory depression. It has also been used for treatment of postoperative shivering.
Last Modified23 July 2010
SubmitterGareth Owen
DownloadsMolfile
FormulaC24H31N2O2.Cl
Net Charge0
Average Mass414.977
Monoisotopic Mass414.20741
SMILESCCN1CC(CC[NH+]2CCOCC2)C(c2ccccc2)(c2ccccc2)C1=O.[Cl-]
InChIInChI=1S/C24H30N2O2.ClH/c1-2-26-19-22(13-14-25-15-17-28-18-16-25)24(23(26)27,20-9-5-3-6-10-20)21-11-7-4-8-12-21;/h3-12,22H,2,13-19H2,1H3;1H
InChIKeyMBGXILHMHYLZJT-UHFFFAOYSA-N
Roles Classification
Application:
central nervous system stimulant  Any drug that enhances the activity of the central nervous system.
ChEBI Ontology
Outgoing Relation(s)
doxapram hydrochloride (anhydrous) (CHEBI:59837) has part doxapram (CHEBI:681848)
doxapram hydrochloride (anhydrous) (CHEBI:59837) has role central nervous system stimulant (CHEBI:35337)
doxapram hydrochloride (anhydrous) (CHEBI:59837) is a hydrochloride (CHEBI:36807)
Incoming Relation(s)
doxapram hydrochloride monohydrate (CHEBI:31520) has part doxapram hydrochloride (anhydrous) (CHEBI:59837)
IUPAC Name 
4-[2-(1-ethyl-5-oxo-4,4-diphenylpyrrolidin-3-yl)ethyl]morpholin-4-ium chloride
Synonyms  Source
1-ethyl-4-[2-(morpholin-4-yl)ethyl]-3,3-diphenylpyrrolidin-2-one hydrochlorideChEBI
doxapram HClChemIDplus
3,3-diphenyl-1-ethyl-4-(2-morpholinoethyl)-2-pyrrolidinone hydrochlorideChemIDplus
doxapram hydrochlorideChemIDplus
(±)-doxapram hydrochloride (anhydrous)ChEBI
(±)-doxapram HClChEBI
Manual XrefsDatabases
DB00561DrugBank
Registry NumbersSources
Beilstein:4171633Beilstein
CAS:113-07-5ChemIDplus