CHEBI:59477 - chloroxine

ChEBI IDCHEBI:59477
ChEBI Namechloroxine
Stars
DefinitionA monohydroxyquinoline that is quinolin-8-ol in which the hydrogens at positions 5 and 7 have been substituted by chlorine. A synthetic antibacterial prepared by chlorination of quinolin-8-ol, it is used for the treatment of dandruff and seborrhoeic dermatitis of the scalp.
Last Modified14 June 2017
SubmitterGareth Owen
DownloadsMolfile
FormulaC9H5Cl2NO
Net Charge0
Average Mass214.051
Monoisotopic Mass212.97482
SMILESOc1c(Cl)cc(Cl)c2cccnc12
InChIInChI=1S/C9H5Cl2NO/c10-6-4-7(11)9(13)8-5(6)2-1-3-12-8/h1-4,13H
InChIKeyWDFKMLRRRCGAKS-UHFFFAOYSA-N
Wikipedia
Roles Classification
Biological Roles:
antibacterial agent  A substance (or active part thereof) that kills or slows the growth of bacteria.
antifungal drug  Any antifungal agent used to prevent or treat fungal infections in humans or animals.
Applications:
antifungal drug  Any antifungal agent used to prevent or treat fungal infections in humans or animals.
antiseborrheic  A drug or agent applied to the skin to control seborrhea or seborrheic dermatitis.
ChEBI Ontology
Outgoing Relation(s)
chloroxine (CHEBI:59477) has functional parent quinolin-8-ol (CHEBI:48981)
chloroxine (CHEBI:59477) has role antibacterial agent (CHEBI:33282)
chloroxine (CHEBI:59477) has role antifungal drug (CHEBI:86327)
chloroxine (CHEBI:59477) has role antiseborrheic (CHEBI:59010)
chloroxine (CHEBI:59477) is a monohydroxyquinoline (CHEBI:38775)
chloroxine (CHEBI:59477) is a organochlorine compound (CHEBI:36683)
IUPAC Name 
5,7-dichloroquinolin-8-ol
Synonyms  Source
5,7-dichlor-8-hydroxychinolinChemIDplus
5,7-dichloro-8-hydroxyquinolineChemIDplus
5,7-dichloro-8-oxyquinolineNIST Chemistry WebBook
5,7-dichloro-8-quinolinolNIST Chemistry WebBook
5,7-dichlorooxineChemIDplus
5,7-dichloroxineNIST Chemistry WebBook
Manual XrefsDatabases
611DrugCentral
ChloroxineWikipedia
D03472KEGG DRUG
DB01243DrugBank
LSM-2371LINCS
Registry NumbersSources
Reaxys:153606Reaxys
CAS:773-76-2ChemIDplus
CAS:773-76-2NIST Chemistry WebBook
Citations