EMBL-EBI | Chemical Biology | ChEBI

Example searches: iron*, InChI=1S/CH4O/c1-2/h2H,1H3, caffeine | Advanced Search

CHEBI:59164 - balsalazide disodium

ChEBI IDCHEBI:59164
ChEBI Namebalsalazide disodium
Stars
DefinitionThe dihydrate of the disodium salt of balsalazide. A prodrug, releasing the anti-inflammatory 5-aminosalicylic acid (mesalazine) in the large intestine, it is used in the treatment of ulcerative colitis.
Last Modified16 April 2010
SubmitterGareth Owen
DownloadsMolfile
FormulaC17H13N3O6.2H2O.2Na
Net Charge0
Average Mass437.316
Monoisotopic Mass437.08110
SMILESO.O.O=C([O-])CCNC(=O)c1ccc(/N=N/c2ccc(O)c(C(=O)[O-])c2)cc1.[Na+].[Na+]
InChIInChI=1S/C17H15N3O6.2Na.2H2O/c21-14-6-5-12(9-13(14)17(25)26)20-19-11-3-1-10(2-4-11)16(24)18-8-7-15(22)23;;;;/h1-6,9,21H,7-8H2,(H,18,24)(H,22,23)(H,25,26);;;2*1H2/q;2*+1;;/p-2/b20-19+;;;;
InChIKeyXDCNKOBSQURQOZ-MVIJUDHYSA-L
Roles Classification
Applications:
anti-ulcer drug  One of various classes of drugs with different action mechanisms used to treat or ameliorate peptic ulcer or irritation of the gastrointestinal tract.
gastrointestinal drug  A drug used for its effects on the gastrointestinal system, e.g. controlling gastric acidity, regulating gastrointestinal motility and water flow, and improving digestion.
non-steroidal anti-inflammatory drug  An anti-inflammatory drug that is not a steroid. In addition to anti-inflammatory actions, non-steroidal anti-inflammatory drugs have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins.
ChEBI Ontology
Outgoing Relation(s)
balsalazide disodium (CHEBI:59164) has functional parent balsalazide (CHEBI:267413)
balsalazide disodium (CHEBI:59164) has part balsalazide(2−) (CHEBI:59165)
balsalazide disodium (CHEBI:59164) has role anti-ulcer drug (CHEBI:49201)
balsalazide disodium (CHEBI:59164) has role gastrointestinal drug (CHEBI:55324)
balsalazide disodium (CHEBI:59164) has role non-steroidal anti-inflammatory drug (CHEBI:35475)
balsalazide disodium (CHEBI:59164) is a hydrate (CHEBI:35505)
balsalazide disodium (CHEBI:59164) is a organic sodium salt (CHEBI:38700)
IUPAC Name 
disodium 5-[(E)-{4-[(2-carboxylatoethyl)carbamoyl]phenyl}diazenyl]-2-hydroxybenzoate—water (1/2)
Synonyms  Source
sodium 5-[(E)-{4-[(2-carboxylatoethyl)carbamoyl]phenyl}diazenyl]-2-hydroxybenzoate hydrate (2:1:2)IUPAC
disodium 5-((4-(((2-carboxyethyl)amino)carbonyl)phenyl)azo)-2-hydroxybenzoate dihydrateChEBI
disodium balsalazideKEGG DRUG
balsalazide sodiumChEBI
disodium 5-[4-(2-carboxyethylcarbamoyl)phenylazo]salicylateChEBI
bisalazine disodiumChEBI
Manual XrefsDatabases
DB01014DrugBank
D02715KEGG DRUG
Registry NumbersSources
Beilstein:8245993Beilstein
CAS:150399-21-6ChemIDplus
CAS:150399-21-6KEGG DRUG