CHEBI:59118 - perazine

ChEBI IDCHEBI:59118
ChEBI Nameperazine
Stars
DefinitionA phenothiazine derivative in which 10H-phenothiazinecarries a 3-(4-methylpiperazin-1-yl)propyl substituent at the N-10 position.
Last Modified22 February 2017
SubmitterSteve
DownloadsMolfile
FormulaC20H25N3S
Net Charge0
Average Mass339.508
Monoisotopic Mass339.17692
SMILESCN1CCN(CCCN2c3ccccc3Sc3ccccc32)CC1
InChIInChI=1S/C20H25N3S/c1-21-13-15-22(16-14-21)11-6-12-23-17-7-2-4-9-19(17)24-20-10-5-3-8-18(20)23/h2-5,7-10H,6,11-16H2,1H3
InChIKeyWEYVCQFUGFRXOM-UHFFFAOYSA-N
Wikipedia
Roles Classification
Chemical Role:
Bronsted base  A molecular entity capable of accepting a hydron from a donor (Brønsted acid).
Biological Role:
dopaminergic antagonist  A drug that binds to but does not activate dopamine receptors, thereby blocking the actions of dopamine or exogenous agonists.
Applications:
antidepressant  Antidepressants are mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions.
antipsychotic agent  Antipsychotic drugs are agents that control agitated psychotic behaviour, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect.
anxiolytic drug  Anxiolytic drugs are agents that alleviate anxiety, tension, and anxiety disorders, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions.
dopaminergic antagonist  A drug that binds to but does not activate dopamine receptors, thereby blocking the actions of dopamine or exogenous agonists.
ChEBI Ontology
Outgoing Relation(s)
perazine (CHEBI:59118) has parent hydride 10H-phenothiazine (CHEBI:37931)
perazine (CHEBI:59118) has role antidepressant (CHEBI:35469)
perazine (CHEBI:59118) has role antipsychotic agent (CHEBI:35476)
perazine (CHEBI:59118) has role anxiolytic drug (CHEBI:35474)
perazine (CHEBI:59118) has role dopaminergic antagonist (CHEBI:48561)
perazine (CHEBI:59118) has role phenothiazine antipsychotic drug (CHEBI:37930)
perazine (CHEBI:59118) is a N-alkylpiperazine (CHEBI:46845)
perazine (CHEBI:59118) is a N-methylpiperazine (CHEBI:46920)
perazine (CHEBI:59118) is a organic molecular entity (CHEBI:50860)
perazine (CHEBI:59118) is a phenothiazines (CHEBI:38093)
Incoming Relation(s)
thiethylperazine (CHEBI:9544) has functional parent perazine (CHEBI:59118)
IUPAC Name 
10-[3-(4-methylpiperazin-1-yl)propyl]-10H-phenothiazine
Synonyms  Source
10-(3-(4-Methyl-1-piperazinyl)propyl)-10H-phenothiazineNIST Chemistry WebBook
N-(3-(4-Methyl-1-piperazinyl)propyl)phenothiazineChemIDplus
N-Methyl-piperazinyl-N'-propyl-phenothiazinChemIDplus
N-Methyl-piperazinylpropyl-phenothiazineNIST Chemistry WebBook
PerazineChEMBL
PernazineChemIDplus
Manual XrefsDatabases
2100DrugCentral
C16903KEGG COMPOUND
GB780193Patent
PerazineWikipedia
Registry NumbersSources
Gmelin:298041Gmelin
Reaxys:39009Reaxys
CAS:84-97-9NIST Chemistry WebBook
CAS:84-97-9KEGG COMPOUND
CAS:84-97-9ChemIDplus
Citations