CHEBI:59118 - perazine

ChEBI IDCHEBI:59118
ChEBI Nameperazine
Stars
DefinitionA phenothiazine derivative in which 10H-phenothiazinecarries a 3-(4-methylpiperazin-1-yl)propyl substituent at the N-10 position.
Last Modified22 February 2017
SubmitterSteve
DownloadsMolfile
FormulaC20H25N3S
Net Charge0
Average Mass339.508
Monoisotopic Mass339.17692
SMILESCN1CCN(CCCN2c3ccccc3Sc3ccccc32)CC1
InChIInChI=1S/C20H25N3S/c1-21-13-15-22(16-14-21)11-6-12-23-17-7-2-4-9-19(17)24-20-10-5-3-8-18(20)23/h2-5,7-10H,6,11-16H2,1H3
InChIKeyWEYVCQFUGFRXOM-UHFFFAOYSA-N
Wikipedia
Roles Classification
Chemical Role:
Bronsted base  A molecular entity capable of accepting a hydron from a donor (Brønsted acid).
Biological Role:
dopaminergic antagonist  A drug that binds to but does not activate dopamine receptors, thereby blocking the actions of dopamine or exogenous agonists.
Applications:
dopaminergic antagonist  A drug that binds to but does not activate dopamine receptors, thereby blocking the actions of dopamine or exogenous agonists.
ChEBI Ontology
Outgoing Relation(s)
perazine (CHEBI:59118) has parent hydride 10H-phenothiazine (CHEBI:37931)
perazine (CHEBI:59118) has role dopaminergic antagonist (CHEBI:48561)
perazine (CHEBI:59118) has role phenothiazine antipsychotic drug (CHEBI:37930)
perazine (CHEBI:59118) is a N-alkylpiperazine (CHEBI:46845)
perazine (CHEBI:59118) is a N-methylpiperazine (CHEBI:46920)
perazine (CHEBI:59118) is a phenothiazines (CHEBI:38093)
Incoming Relation(s)
thiethylperazine (CHEBI:9544) has functional parent perazine (CHEBI:59118)
IUPAC Name 
10-[3-(4-methylpiperazin-1-yl)propyl]-10H-phenothiazine
Synonyms  Source
N-(3-(4-Methyl-1-piperazinyl)propyl)phenothiazineChemIDplus
N-Methyl-piperazinyl-N'-propyl-phenothiazinChemIDplus
PernazineChemIDplus
N-Methyl-piperazinylpropyl-phenothiazineNIST Chemistry WebBook
10-(3-(4-Methyl-1-piperazinyl)propyl)-10H-phenothiazineNIST Chemistry WebBook
Manual XrefsDatabases
C16903KEGG COMPOUND
GB780193Patent
PerazineWikipedia
2100DrugCentral
Registry NumbersSources
Gmelin:298041Gmelin
Reaxys:39009Reaxys
CAS:84-97-9KEGG COMPOUND
CAS:84-97-9ChemIDplus
CAS:84-97-9NIST Chemistry WebBook
Citations