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CHEBI:5801 - hydroxychloroquine

ChEBI IDCHEBI:5801
ChEBI Namehydroxychloroquine
Stars
DefinitionAn aminoquinoline that is chloroquine in which one of the N-ethyl groups is hydroxylated at position 2. An antimalarial with properties similar to chloroquine that acts against erythrocytic forms of malarial parasites, it is mainly used as the sulfate salt for the treatment of lupus erythematosus, rheumatoid arthritis, and light-sensitive skin eruptions.
Last Modified30 April 2020
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FormulaC18H26ClN3O
Net Charge0
Average Mass335.879
Monoisotopic Mass335.17644
SMILESCCN(CCO)CCCC(C)Nc1ccnc2cc(Cl)ccc12
InChIInChI=1S/C18H26ClN3O/c1-3-22(11-12-23)10-4-5-14(2)21-17-8-9-20-18-13-15(19)6-7-16(17)18/h6-9,13-14,23H,3-5,10-12H2,1-2H3,(H,20,21)
InChIKeyXXSMGPRMXLTPCZ-UHFFFAOYSA-N

Wikipedia
Roles Classification

ChEBI Ontology
IUPAC Name 
2-[{4-[(7-chloroquinolin-4-yl)amino]pentyl}(ethyl)amino]ethanol
INNs  Source
hydroxychloroquine  frWHO MedNet
hidroxicloroquina  esChemIDplus
hydroxychloroquineChemIDplus
hydroxychloroquinum  laChemIDplus
Synonyms  Source
2-(N-(4-(7-chlor-4-chinolylamino)-4-methylbutyl)ethylamino)ethanolChemIDplus
7-chloro-4-(4-(N-ethyl-N-β-hydroxyethylamino)-1-methylbutylamino)quinolineChemIDplus
7-chloro-4-(4-(ethyl(2-hydroxyethyl)amino)-1-methylbutylamino)quinolineChemIDplus
2-((4-((7-chloro-4-quinolyl)amino)pentyl)ethylamino)ethanolChemIDplus
oxichloroquineChEBI
7-chloro-4-[4-(N-ethyl-N-β-hydroxyethylamino)-1-methylbutylamino]quinolineChEBI
Brand Name  Source
PolirreuminKEGG DRUG
Manual XrefsDatabases
C07043KEGG COMPOUND
D08050KEGG DRUG
US2546658Patent
DB01611DrugBank
HMDB0015549HMDB
HydroxychloroquineWikipedia
LSM-5193LINCS
1395DrugCentral
Registry NumbersSources
Reaxys:253894Reaxys
CAS:118-42-3KEGG COMPOUND
CAS:118-42-3ChemIDplus
CAS:118-42-3NIST Chemistry WebBook
Citations