EMBL-EBI | Chemical Biology | ChEBI
Example searches: iron*, InChI=1S/CH4O/c1-2/h2H,1H3, caffeine | Advanced Search
CHEBI:57457 - (6S)-5-formyltetrahydrofolate(2−)
| Formula | C20H21N7O7 |
| Net Charge | -2 |
| Average Mass | 471.430 |
| Monoisotopic Mass | 471.15134 |
| SMILES | [H]C(=O)N1c2c(nc(N)nc2=O)NC[C@@H]1CNc1ccc(C(=O)N[C@@H](CCC(=O)[O-])C(=O)[O-])cc1 |
| InChI | InChI=1S/C20H23N7O7/c21-20-25-16-15(18(32)26-20)27(9-28)12(8-23-16)7-22-11-3-1-10(2-4-11)17(31)24-13(19(33)34)5-6-14(29)30/h1-4,9,12-13,22H,5-8H2,(H,24,31)(H,29,30)(H,33,34)(H4,21,23,25,26,32)/p-2/t12-,13-/m0/s1 |
| InChIKey | VVIAGPKUTFNRDU-STQMWFEESA-L |
| Species of Metabolite | Component | Source | Comments |
|---|---|---|---|
| Homo sapiens (ncbitaxon:9606) | - | DOI (10.1038/nbt.2488) | |
| Saccharomyces cerevisiae (ncbitaxon:4932) | - | PubMed (24678285) | Source: yeast.sf.net |
| Roles Classification |
|---|
| Biological Roles: | human metabolite Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens). Saccharomyces cerevisiae metabolite Any fungal metabolite produced during a metabolic reaction in Baker's yeast (Saccharomyces cerevisiae ). |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| (6S)-5-formyltetrahydrofolate(2−) (CHEBI:57457) has role Saccharomyces cerevisiae metabolite (CHEBI:75772) |
| (6S)-5-formyltetrahydrofolate(2−) (CHEBI:57457) has role human metabolite (CHEBI:77746) |
| (6S)-5-formyltetrahydrofolate(2−) (CHEBI:57457) is a dicarboxylic acid dianion (CHEBI:28965) |
| (6S)-5-formyltetrahydrofolate(2−) (CHEBI:57457) is conjugate base of (6S)-5-formyltetrahydrofolic acid (CHEBI:63606) |
| Incoming Relation(s) |
| (6S)-5-formyltetrahydrofolic acid (CHEBI:63606) is conjugate acid of (6S)-5-formyltetrahydrofolate(2−) (CHEBI:57457) |
| IUPAC Name |
|---|
| N-[4-({[(6S)-2-amino-5-formyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamate |
| Synonym | Source |
|---|---|
| 5-formyltetrahydrofolate dianion | ChEBI |
| UniProt Name | Source |
|---|---|
| (6S)-5-formyl-5,6,7,8-tetrahydrofolate | UniProt |
| Manual Xrefs | Databases |
|---|---|
| 5-FORMYL-THF | MetaCyc |
| Registry Numbers | Sources |
|---|---|
| Beilstein:3923649 | Beilstein |