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CHEBI:5494 - ritropirronium bromide
| ChEBI ID | CHEBI:5494 |
| ChEBI Name | ritropirronium bromide |
| Stars | |
| Definition | A racemate composed of equimolar amounts of (2S,3R)- and (2S,3R)-glycopyrronium bromide. Used either alone or in combination therapy for maintenance treatment of airflow obstruction in patients with chronic obstructive pulmonary disease. |
| Last Modified | 16 August 2016 |
| Formula | C19H28BrNO3 |
| Net Charge | 0 |
| Average Mass | 398.335 |
| Monoisotopic Mass | 397.12526 |
| Wikipedia |
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| Roles Classification |
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| Biological Role: | muscarinic antagonist A drug that binds to but does not activate muscarinic cholinergic receptors, thereby blocking the actions of endogenous acetylcholine or exogenous agonists. |
| Applications: | bronchodilator agent An agent that causes an increase in the expansion of a bronchus or bronchial tubes. muscarinic antagonist A drug that binds to but does not activate muscarinic cholinergic receptors, thereby blocking the actions of endogenous acetylcholine or exogenous agonists. |
| ChEBI Ontology |
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| Outgoing Relation(s) |
| ritropirronium bromide (CHEBI:5494) has part (2R,3S)-glycopyrronium bromide (CHEBI:90974) |
| ritropirronium bromide (CHEBI:5494) has part (2S,3R)-glycopyrronium bromide (CHEBI:90973) |
| ritropirronium bromide (CHEBI:5494) has role bronchodilator agent (CHEBI:35523) |
| ritropirronium bromide (CHEBI:5494) has role muscarinic antagonist (CHEBI:48876) |
| ritropirronium bromide (CHEBI:5494) is a racemate (CHEBI:60911) |
| Incoming Relation(s) |
| Bevespi Aerosphere (CHEBI:133025) has part ritropirronium bromide (CHEBI:5494) |
| Utibron Neohaler (CHEBI:90962) has part ritropirronium bromide (CHEBI:5494) |
| IUPAC Name |
|---|
| rac-(3R)-3-{[(2S)-2-cyclopentyl-2-hydroxy-2-phenylacetyl]oxy}-1,1-dimethylpyrrolidin-1-ium bromide |
| INNs | Source |
|---|---|
| glycopyrronium bromide | KEGG DRUG |
| ritropirronium bromide | ChemIDplus |
| Synonyms | Source |
|---|---|
| 3-Hydroxy-1,1-dimethylpyrrolidinium bromide alpha-cyclopentylmandelate | ChemIDplus |
| (3RS)-3-{[(2SR)-2-cyclopentyl-2-hydroxy-2-phenylacetyl]oxy}-1,1-dimethylpyrrolidin-1-ium bromide | ChEBI |
| erythro-Glycopyrronium bromide | ChemIDplus |
| Glycopyrrolate | KEGG DRUG |
| Manual Xrefs | Databases |
|---|---|
| D00540 | KEGG DRUG |
| DB00986 | DrugBank |
| Glycopyrronium_bromide | Wikipedia |
| Registry Numbers | Sources |
|---|---|
| Reaxys:14616835 | Reaxys |
| CAS:51186-83-5 | ChemIDplus |
| Citations |
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