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CHEBI:53770 - aceprometazine

Default Structure
ChEBI IDCHEBI:53770
ChEBI Nameaceprometazine
Stars
DefinitionA phenothiazine compound having an acetyl group at the 2-position and a 2-(dimethylamino)-1-propyl group at the 10-position.
Last Modified22 February 2017
SubmitterSteve
DownloadsMolfile
FormulaC19H22N2OS
Net Charge0
Average Mass326.465
Monoisotopic Mass326.14528
SMILESCC(=O)c1ccc2c(c1)N(CC(C)N(C)C)c1ccccc1S2
InChIInChI=1S/C19H22N2OS/c1-13(20(3)4)12-21-16-7-5-6-8-18(16)23-19-10-9-15(14(2)22)11-17(19)21/h5-11,13H,12H2,1-4H3
InChIKeyXLOQNFNTQIRSOX-UHFFFAOYSA-N
Wikipedia
Roles Classification
Chemical Role:
Bronsted base  A molecular entity capable of accepting a hydron from a donor (Brønsted acid).
Biological Role:
histamine antagonist  Histamine antagonists are the drugs that bind to but do not activate histamine receptors, thereby blocking the actions of histamine or histamine agonists.
Applications:
sedative  A central nervous system depressant used to induce drowsiness or sleep or to reduce psychological excitement or anxiety.
anxiolytic drug  Anxiolytic drugs are agents that alleviate anxiety, tension, and anxiety disorders, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions.
histamine antagonist  Histamine antagonists are the drugs that bind to but do not activate histamine receptors, thereby blocking the actions of histamine or histamine agonists.
ChEBI Ontology
Outgoing Relation(s)
aceprometazine (CHEBI:53770) has role anxiolytic drug (CHEBI:35474)
aceprometazine (CHEBI:53770) has role histamine antagonist (CHEBI:37956)
aceprometazine (CHEBI:53770) has role sedative (CHEBI:35717)
aceprometazine (CHEBI:53770) is a aromatic ketone (CHEBI:76224)
aceprometazine (CHEBI:53770) is a methyl ketone (CHEBI:51867)
aceprometazine (CHEBI:53770) is a phenothiazines (CHEBI:38093)
aceprometazine (CHEBI:53770) is a tertiary amine (CHEBI:32876)
Incoming Relation(s)
(R)-aceprometazine (CHEBI:53771) is a aceprometazine (CHEBI:53770)
(S)-aceprometazine (CHEBI:53772) is a aceprometazine (CHEBI:53770)
IUPAC Name 
1-{10-[2-(dimethylamino)propyl]-10H-phenothiazin-2-yl}ethanone
INNs  Source
aceprometazinaDrugBank
aceprometazineDrugBank
acéprométazineWHO MedNet
aceprometazinumDrugBank
Synonyms  Source
10-(2-(Dimethylamino)propyl)phenothiazin-2-yl methyl ketoneChEBI
AcepromethazineChemIDplus
Manual XrefsDatabases
50DrugCentral
AceprometazineWikipedia
DB01615DrugBank
Registry NumbersSources
Reaxys:38528Reaxys
CAS:13461-01-3NIST Chemistry WebBook
CAS:13461-01-3DrugBank
CAS:13461-01-3ChemIDplus