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CHEBI:15414 - S-adenosyl-L-methionine
| Formula | C15H23N6O5S |
| Net Charge | +1 |
| Average Mass | 399.453 |
| Monoisotopic Mass | 399.14452 |
| SMILES | C[S+](CC[C@H](N)C(=O)O)C[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O |
| InChI | InChI=1S/C15H22N6O5S/c1-27(3-2-7(16)15(24)25)4-8-10(22)11(23)14(26-8)21-6-20-9-12(17)18-5-19-13(9)21/h5-8,10-11,14,22-23H,2-4,16H2,1H3,(H2-,17,18,19,24,25)/p+1/t7-,8+,10+,11+,14+,27?/m0/s1 |
| InChIKey | MEFKEPWMEQBLKI-AIRLBKTGSA-O |
| Wikipedia |
|---|
| Species of Metabolite | Component | Source | Comments |
|---|---|---|---|
| Homo sapiens (ncbitaxon:9606) | - | DOI (10.1038/nbt.2488) | |
| Saccharomyces cerevisiae (ncbitaxon:4932) | - | PubMed (24678285) | Source: yeast.sf.net |
| Mycoplasma genitalium (ncbitaxon:2097) | - | PubMed (22817898) |
| Roles Classification |
|---|
| Biological Roles: | cofactor An organic molecule or ion (usually a metal ion) that is required by an enzyme for its activity. It may be attached either loosely (coenzyme) or tightly (prosthetic group). human metabolite Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens). Mycoplasma genitalium metabolite Any bacterial metabolite produced during a metabolic reaction in Mycoplasma genitalium. Saccharomyces cerevisiae metabolite Any fungal metabolite produced during a metabolic reaction in Baker's yeast (Saccharomyces cerevisiae ). micronutrient Any nutrient required in small quantities by organisms throughout their life in order to orchestrate a range of physiological functions. coenzyme A low-molecular-weight, non-protein organic compound participating in enzymatic reactions as dissociable acceptor or donor of chemical groups or electrons. |
| Application: | nutraceutical A product in capsule, tablet or liquid form that provide essential nutrients, such as a vitamin, an essential mineral, a protein, an herb, or similar nutritional substance. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| S-adenosyl-L-methionine (CHEBI:15414) has role Mycoplasma genitalium metabolite (CHEBI:131604) |
| S-adenosyl-L-methionine (CHEBI:15414) has role Saccharomyces cerevisiae metabolite (CHEBI:75772) |
| S-adenosyl-L-methionine (CHEBI:15414) has role coenzyme (CHEBI:23354) |
| S-adenosyl-L-methionine (CHEBI:15414) has role cofactor (CHEBI:23357) |
| S-adenosyl-L-methionine (CHEBI:15414) has role human metabolite (CHEBI:77746) |
| S-adenosyl-L-methionine (CHEBI:15414) has role micronutrient (CHEBI:27027) |
| S-adenosyl-L-methionine (CHEBI:15414) has role nutraceutical (CHEBI:50733) |
| S-adenosyl-L-methionine (CHEBI:15414) is a sulfonium compound (CHEBI:26830) |
| S-adenosyl-L-methionine (CHEBI:15414) is conjugate acid of S-adenosyl-L-methioninate (CHEBI:67040) |
| S-adenosyl-L-methionine (CHEBI:15414) is tautomer of S-adenosyl-L-methionine zwitterion (CHEBI:59789) |
| Incoming Relation(s) |
| S-adenosyl-S-carboxymethyl-L-homocysteine (CHEBI:136699) has functional parent S-adenosyl-L-methionine (CHEBI:15414) |
| (R)-S-adenosyl-L-methionine (CHEBI:33440) is a S-adenosyl-L-methionine (CHEBI:15414) |
| (S)-S-adenosyl-L-methionine (CHEBI:33442) is a S-adenosyl-L-methionine (CHEBI:15414) |
| S-adenosyl-L-methioninate (CHEBI:67040) is conjugate base of S-adenosyl-L-methionine (CHEBI:15414) |
| S-adenosyl-L-methionine zwitterion (CHEBI:59789) is tautomer of S-adenosyl-L-methionine (CHEBI:15414) |
| IUPAC Name |
|---|
| [(3S)-3-amino-3-carboxypropyl](5'-deoxyadenosin-5'-yl)(methyl)sulfonium |
| Synonyms | Source |
|---|---|
| S-Adenosyl-L-methionine | KEGG COMPOUND |
| S-Adenosylmethionine | KEGG COMPOUND |
| Acylcarnitine | KEGG COMPOUND |
| S-(5'-deoxyadenosin-5'-yl)-L-methionine | JCBN |
| AdoMet | JCBN |
| SAM | JCBN |
| Manual Xrefs | Databases |
|---|---|
| C00019 | KEGG COMPOUND |
| C00019 | KEGG COMPOUND |
| S-Adenosyl_methionine | Wikipedia |
| S-ADENOSYLMETHIONINE | MetaCyc |
| DB00118 | DrugBank |
| HMDB0001185 | HMDB |
| C00007347 | KNApSAcK |
| Registry Numbers | Sources |
|---|---|
| Beilstein:3576439 | Beilstein |
| Reaxys:3919754 | Reaxys |
| CAS:29908-03-0 | KEGG COMPOUND |
| CAS:29908-03-0 | ChemIDplus |
| Citations |
|---|