EMBL-EBI | Chemical Biology | ChEBI
Example searches: iron*, InChI=1S/CH4O/c1-2/h2H,1H3, caffeine | Advanced Search
CHEBI:15414 - S-adenosyl-L-methionine
| Formula | C15H23N6O5S |
| Net Charge | +1 |
| Average Mass | 399.453 |
| Monoisotopic Mass | 399.14452 |
| SMILES | C[S+](CC[C@H](N)C(=O)O)C[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O |
| InChI | InChI=1S/C15H22N6O5S/c1-27(3-2-7(16)15(24)25)4-8-10(22)11(23)14(26-8)21-6-20-9-12(17)18-5-19-13(9)21/h5-8,10-11,14,22-23H,2-4,16H2,1H3,(H2-,17,18,19,24,25)/p+1/t7-,8+,10+,11+,14+,27?/m0/s1 |
| InChIKey | MEFKEPWMEQBLKI-AIRLBKTGSA-O |
| Wikipedia |
|---|
| Species of Metabolite | Component | Source | Comments |
|---|---|---|---|
| Homo sapiens (ncbitaxon:9606) | - | DOI (10.1038/nbt.2488) | |
| Saccharomyces cerevisiae (ncbitaxon:4932) | - | PubMed (24678285) | Source: yeast.sf.net |
| Mycoplasma genitalium (ncbitaxon:2097) | - | PubMed (22817898) |
| Roles Classification |
|---|
| Biological Roles: | Mycoplasma genitalium metabolite Any bacterial metabolite produced during a metabolic reaction in Mycoplasma genitalium. human metabolite Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens). Saccharomyces cerevisiae metabolite Any fungal metabolite produced during a metabolic reaction in Baker's yeast (Saccharomyces cerevisiae ). cofactor An organic molecule or ion (usually a metal ion) that is required by an enzyme for its activity. It may be attached either loosely (coenzyme) or tightly (prosthetic group). coenzyme A low-molecular-weight, non-protein organic compound participating in enzymatic reactions as dissociable acceptor or donor of chemical groups or electrons. micronutrient Any nutrient required in small quantities by organisms throughout their life in order to orchestrate a range of physiological functions. |
| Application: | nutraceutical A product in capsule, tablet or liquid form that provide essential nutrients, such as a vitamin, an essential mineral, a protein, an herb, or similar nutritional substance. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| S-adenosyl-L-methionine (CHEBI:15414) has role Mycoplasma genitalium metabolite (CHEBI:131604) |
| S-adenosyl-L-methionine (CHEBI:15414) has role Saccharomyces cerevisiae metabolite (CHEBI:75772) |
| S-adenosyl-L-methionine (CHEBI:15414) has role coenzyme (CHEBI:23354) |
| S-adenosyl-L-methionine (CHEBI:15414) has role cofactor (CHEBI:23357) |
| S-adenosyl-L-methionine (CHEBI:15414) has role human metabolite (CHEBI:77746) |
| S-adenosyl-L-methionine (CHEBI:15414) has role micronutrient (CHEBI:27027) |
| S-adenosyl-L-methionine (CHEBI:15414) has role nutraceutical (CHEBI:50733) |
| S-adenosyl-L-methionine (CHEBI:15414) is a sulfonium compound (CHEBI:26830) |
| S-adenosyl-L-methionine (CHEBI:15414) is conjugate acid of S-adenosyl-L-methioninate (CHEBI:67040) |
| S-adenosyl-L-methionine (CHEBI:15414) is tautomer of S-adenosyl-L-methionine zwitterion (CHEBI:59789) |
| Incoming Relation(s) |
| S-adenosyl-S-carboxymethyl-L-homocysteine (CHEBI:136699) has functional parent S-adenosyl-L-methionine (CHEBI:15414) |
| (R)-S-adenosyl-L-methionine (CHEBI:33440) is a S-adenosyl-L-methionine (CHEBI:15414) |
| (S)-S-adenosyl-L-methionine (CHEBI:33442) is a S-adenosyl-L-methionine (CHEBI:15414) |
| S-adenosyl-L-methioninate (CHEBI:67040) is conjugate base of S-adenosyl-L-methionine (CHEBI:15414) |
| S-adenosyl-L-methionine zwitterion (CHEBI:59789) is tautomer of S-adenosyl-L-methionine (CHEBI:15414) |
| IUPAC Name |
|---|
| [(3S)-3-amino-3-carboxypropyl](5'-deoxyadenosin-5'-yl)(methyl)sulfonium |
| Synonyms | Source |
|---|---|
| S-Adenosyl-L-methionine | KEGG COMPOUND |
| S-Adenosylmethionine | KEGG COMPOUND |
| Acylcarnitine | KEGG COMPOUND |
| S-(5'-deoxyadenosin-5'-yl)-L-methionine | JCBN |
| AdoMet | JCBN |
| SAM | JCBN |
| Manual Xrefs | Databases |
|---|---|
| C00019 | KEGG COMPOUND |
| C00019 | KEGG COMPOUND |
| S-Adenosyl_methionine | Wikipedia |
| S-ADENOSYLMETHIONINE | MetaCyc |
| DB00118 | DrugBank |
| HMDB0001185 | HMDB |
| C00007347 | KNApSAcK |
| Registry Numbers | Sources |
|---|---|
| Beilstein:3576439 | Beilstein |
| Reaxys:3919754 | Reaxys |
| CAS:29908-03-0 | KEGG COMPOUND |
| CAS:29908-03-0 | ChemIDplus |
| Citations |
|---|