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CHEBI:521051 - (R)-fenfluramine
| Formula | C12H16F3N |
| Net Charge | 0 |
| Average Mass | 231.261 |
| Monoisotopic Mass | 231.12348 |
| SMILES | CCN[C@H](C)Cc1cccc(C(F)(F)F)c1 |
| InChI | InChI=1S/C12H16F3N/c1-3-16-9(2)7-10-5-4-6-11(8-10)12(13,14)15/h4-6,8-9,16H,3,7H2,1-2H3/t9-/m1/s1 |
| InChIKey | DBGIVFWFUFKIQN-SECBINFHSA-N |
| Roles Classification |
|---|
| Chemical Roles: | Bronsted base A molecular entity capable of accepting a hydron from a donor (Brønsted acid). Bronsted base A molecular entity capable of accepting a hydron from a donor (Brønsted acid). |
| Biological Roles: | serotonin uptake inhibitor A compound that specifically inhibits the reuptake of serotonin in the brain. This increases the serotonin concentration in the synaptic cleft which then activates serotonin receptors to a greater extent. serotonergic agonist An agent that has an affinity for serotonin receptors and is able to mimic the effects of serotonin by stimulating the physiologic activity at the cell receptors. Serotonin agonists are used as antidepressants, anxiolytics, and in the treatment of migraine disorders. |
| Applications: | appetite depressant Any agent that is used to decrease appetite. serotonin uptake inhibitor A compound that specifically inhibits the reuptake of serotonin in the brain. This increases the serotonin concentration in the synaptic cleft which then activates serotonin receptors to a greater extent. serotonergic agonist An agent that has an affinity for serotonin receptors and is able to mimic the effects of serotonin by stimulating the physiologic activity at the cell receptors. Serotonin agonists are used as antidepressants, anxiolytics, and in the treatment of migraine disorders. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| (R)-fenfluramine (CHEBI:521051) is a fenfluramine (CHEBI:5000) |
| (R)-fenfluramine (CHEBI:521051) is enantiomer of (S)-fenfluramine (CHEBI:439329) |
| Incoming Relation(s) |
| (S)-fenfluramine (CHEBI:439329) is enantiomer of (R)-fenfluramine (CHEBI:521051) |
| IUPAC Name |
|---|
| (2R)-N-ethyl-1-[3-(trifluoromethyl)phenyl]propan-2-amine |
| INNs | Source |
|---|---|
| (R)-fenfluramine | ChEBI |
| levofenfluramina | ChemIDplus |
| levofenfluramine | ChemIDplus |
| levofenfluraminum | ChemIDplus |
| Synonyms | Source |
|---|---|
| (−)-fenfluramine | ChEBI |
| (R)-N-ethyl-1-[3-(trifluoromethyl)phenyl]propan-2-amine | ChEBI |
| Registry Numbers | Sources |
|---|---|
| Beilstein:4783711 | Beilstein |
| CAS:37577-24-5 | ChemIDplus |
| Citations |
|---|