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CHEBI:521051 - (R)-fenfluramine
| Formula | C12H16F3N |
| Net Charge | 0 |
| Average Mass | 231.261 |
| Monoisotopic Mass | 231.12348 |
| SMILES | CCN[C@H](C)Cc1cccc(C(F)(F)F)c1 |
| InChI | InChI=1S/C12H16F3N/c1-3-16-9(2)7-10-5-4-6-11(8-10)12(13,14)15/h4-6,8-9,16H,3,7H2,1-2H3/t9-/m1/s1 |
| InChIKey | DBGIVFWFUFKIQN-SECBINFHSA-N |
| Roles Classification |
|---|
| Chemical Roles: | Bronsted base A molecular entity capable of accepting a hydron from a donor (Brønsted acid). Bronsted base A molecular entity capable of accepting a hydron from a donor (Brønsted acid). |
| Biological Roles: | serotonin uptake inhibitor A compound that specifically inhibits the reuptake of serotonin in the brain. This increases the serotonin concentration in the synaptic cleft which then activates serotonin receptors to a greater extent. anti-obesity agent Any substance which is used to reduce or control weight. serotonergic agonist An agent that has an affinity for serotonin receptors and is able to mimic the effects of serotonin by stimulating the physiologic activity at the cell receptors. Serotonin agonists are used as antidepressants, anxiolytics, and in the treatment of migraine disorders. |
| Applications: | serotonin uptake inhibitor A compound that specifically inhibits the reuptake of serotonin in the brain. This increases the serotonin concentration in the synaptic cleft which then activates serotonin receptors to a greater extent. appetite depressant Any agent that is used to decrease appetite. anticonvulsant A drug used to prevent seizures or reduce their severity. antispasmodic drug A drug that suppresses spasms. These are usually caused by smooth muscle contraction, especially in tubular organs. The effect is to prevent spasms of the stomach, intestine or urinary bladder. serotonergic agonist An agent that has an affinity for serotonin receptors and is able to mimic the effects of serotonin by stimulating the physiologic activity at the cell receptors. Serotonin agonists are used as antidepressants, anxiolytics, and in the treatment of migraine disorders. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| (R)-fenfluramine (CHEBI:521051) is a fenfluramine (CHEBI:5000) |
| (R)-fenfluramine (CHEBI:521051) is enantiomer of (S)-fenfluramine (CHEBI:439329) |
| Incoming Relation(s) |
| (S)-fenfluramine (CHEBI:439329) is enantiomer of (R)-fenfluramine (CHEBI:521051) |
| IUPAC Name |
|---|
| (2R)-N-ethyl-1-[3-(trifluoromethyl)phenyl]propan-2-amine |
| INNs | Source |
|---|---|
| (R)-fenfluramine | ChEBI |
| levofenfluramina | ChemIDplus |
| levofenfluramine | ChemIDplus |
| levofenfluraminum | ChemIDplus |
| Synonyms | Source |
|---|---|
| (−)-fenfluramine | ChEBI |
| Fenfluramine, l- | ChEMBL |
| Fenfluramine l-form | ChEMBL |
| (R)-N-ethyl-1-[3-(trifluoromethyl)phenyl]propan-2-amine | ChEBI |
| J50.055K | ChEMBL |
| levofenfluramine | ChEMBL |
| Registry Numbers | Sources |
|---|---|
| Beilstein:4783711 | Beilstein |
| CAS:37577-24-5 | ChemIDplus |
| Citations |
|---|