EMBL-EBI | Chemical Biology | ChEBI
Example searches: iron*, InChI=1S/CH4O/c1-2/h2H,1H3, caffeine | Advanced Search
CHEBI:5119 - fluoxetine hydrochloride
| ChEBI ID | CHEBI:5119 |
| ChEBI Name | fluoxetine hydrochloride |
| Stars | |
| Definition | A racemate comprising equimolar amounts of (R)- and (S)-fluoxetine hydrochloride. A selective serotonin reuptake inhibitor (SSRI), it is used for the treatment of depression (and the depressive phase of bipolar disorder), bullimia nervosa, and obsessive-compulsive disorder. |
| Last Modified | 20 July 2015 |
| Formula | C17H19ClF3NO |
| Net Charge | 0 |
| Average Mass | 345.787 |
| Monoisotopic Mass | 345.11073 |
| Wikipedia |
|---|
| Roles Classification |
|---|
| Biological Roles: | analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. serotonin uptake inhibitor A compound that specifically inhibits the reuptake of serotonin in the brain. This increases the serotonin concentration in the synaptic cleft which then activates serotonin receptors to a greater extent. |
| Applications: | analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. antidepressant Antidepressants are mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. serotonin uptake inhibitor A compound that specifically inhibits the reuptake of serotonin in the brain. This increases the serotonin concentration in the synaptic cleft which then activates serotonin receptors to a greater extent. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| fluoxetine hydrochloride (CHEBI:5119) has part (R)-fluoxetine hydrochloride (CHEBI:86996) |
| fluoxetine hydrochloride (CHEBI:5119) has part (S)-fluoxetine hydrochloride (CHEBI:86997) |
| fluoxetine hydrochloride (CHEBI:5119) has role analgesic (CHEBI:35480) |
| fluoxetine hydrochloride (CHEBI:5119) has role antidepressant (CHEBI:35469) |
| fluoxetine hydrochloride (CHEBI:5119) has role serotonin uptake inhibitor (CHEBI:50949) |
| fluoxetine hydrochloride (CHEBI:5119) is a racemate (CHEBI:60911) |
| IUPAC Name |
|---|
| rac-N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine hydrochloride |
| Synonyms | Source |
|---|---|
| 3-(p-trifluoromethylphenoxy)-N-methyl-3-phenylpropylamine hydrochloride | ChemIDplus |
| (±)-N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propylamine hydrochloride | ChemIDplus |
| rac-fluoxetine hydrochloride | ChEBI |
| (±)-fluoxetine HCl | ChEBI |
| fluoxetine HCl | ChemIDplus |
| (±)-fluoxetine hydrochloride | ChEBI |
| Brand Names | Source |
|---|---|
| Adofen | ChemIDplus |
| Affectine | ChemIDplus |
| Ansilan | ChemIDplus |
| Deproxin | ChemIDplus |
| Digassim | ChemIDplus |
| Erocap | ChemIDplus |
| Manual Xrefs | Databases |
|---|---|
| D00823 | KEGG DRUG |
| DB00472 | DrugBank |
| Fluoxetine | Wikipedia |
| Registry Numbers | Sources |
|---|---|
| Reaxys:27994391 | Reaxys |
| Reaxys:6759273 | Reaxys |
| CAS:56296-78-7 | ChemIDplus |
| CAS:59333-67-4 | KEGG DRUG |
| Citations |
|---|