CHEBI:50931 - (Z)-chlorprothixene

ChEBI IDCHEBI:50931
ChEBI Name(Z)-chlorprothixene
Stars
ASCII Name(Z)-chlorprothixene
DefinitionA chlorprothixene in which the double bond adopts a (Z)-configuration.
Last Modified23 September 2021
SubmitterInma Spiteri
DownloadsMolfile
FormulaC18H18ClNS
Net Charge0
Average Mass315.869
Monoisotopic Mass315.08485
SMILES[H]/C(CCN(C)C)=C1\c2ccccc2Sc2ccc(Cl)cc21
InChIInChI=1S/C18H18ClNS/c1-20(2)11-5-7-14-15-6-3-4-8-17(15)21-18-10-9-13(19)12-16(14)18/h3-4,6-10,12H,5,11H2,1-2H3/b14-7-
InChIKeyWSPOMRSOLSGNFJ-AUWJEWJLSA-N
Wikipedia
Roles Classification
Chemical Roles:
Bronsted base  A molecular entity capable of accepting a hydron from a donor (Brønsted acid).
Bronsted base  A molecular entity capable of accepting a hydron from a donor (Brønsted acid).
Biological Roles:
non-narcotic analgesic  A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors.
dopaminergic antagonist  A drug that binds to but does not activate dopamine receptors, thereby blocking the actions of dopamine or exogenous agonists.
cholinergic antagonist  Any drug that binds to but does not activate cholinergic receptors, thereby blocking the actions of acetylcholine or cholinergic agonists.
Applications:
sedative  A central nervous system depressant used to induce drowsiness or sleep or to reduce psychological excitement or anxiety.
first generation antipsychotic  Antipsychotic drugs which can have different modes of action but which tend to be more likely than second generation antipsychotics to cause extrapyramidal motor control disabilities such as body rigidity or Parkinson's disease-type movements; such body movements can become permanent even after treatment has ceased.
antiemetic  A drug used to prevent nausea or vomiting. An antiemetic may act by a wide range of mechanisms: it might affect the medullary control centres (the vomiting centre and the chemoreceptive trigger zone) or affect the peripheral receptors.
non-narcotic analgesic  A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors.
dopaminergic antagonist  A drug that binds to but does not activate dopamine receptors, thereby blocking the actions of dopamine or exogenous agonists.
cholinergic antagonist  Any drug that binds to but does not activate cholinergic receptors, thereby blocking the actions of acetylcholine or cholinergic agonists.
ChEBI Ontology
Outgoing Relation(s)
(Z)-chlorprothixene (CHEBI:50931) is a chlorprothixene (CHEBI:3651)
IUPAC Name 
(3Z)-3-(2-chloro-9H-thioxanthen-9-ylidene)-N,N-dimethylpropan-1-amine
INNs  Source
ChlorprothixenumChEBI
ClorprotixenoChEBI
Synonyms  Source
(3Z)-3-(2-chloro-9H-thioxanthen-9-ylidene)-N,N-dimethyl-1-propanamineChEBI
ChlorprothixeneChemIDplus
cis-2-Chloro-9-(3-dimethylaminopropylidene)thioxantheneChemIDplus
cis-chlorprothixeneChEBI
(Z)-2-Chloro-9-(omega-dimethylaminopropylidene)thioxantheneChemIDplus
Manual XrefsDatabases
623DrugCentral
C07953KEGG COMPOUND
ChlorprothixeneWikipedia
D00790KEGG DRUG
DB01239DrugBank
Registry NumbersSources
Beilstein:9208755Beilstein
CAS:113-59-7NIST Chemistry WebBook
CAS:113-59-7ChemIDplus
Citations