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CHEBI:4907 - etidronic acid

ChEBI IDCHEBI:4907
ChEBI Nameetidronic acid
Stars
DefinitionA 1,1-bis(phosphonic acid) that is (ethane-1,1-diyl)bis(phosphonic acid) having a hydroxy substituent at the 1-position. It inhibits the formation, growth, and dissolution of hydroxyapatite crystals by chemisorption to calcium phosphate surfaces.
Secondary ChEBI IDCHEBI:63588
Last Modified22 February 2017
DownloadsMolfile
FormulaC2H8O7P2
Net Charge0
Average Mass206.027
Monoisotopic Mass205.97453
SMILESCC(O)(P(=O)(O)O)P(=O)(O)O
InChIInChI=1S/C2H8O7P2/c1-2(3,10(4,5)6)11(7,8)9/h3H,1H3,(H2,4,5,6)(H2,7,8,9)
InChIKeyDBVJJBKOTRCVKF-UHFFFAOYSA-N
Wikipedia
Roles Classification
Chemical Role:
chelator  A ligand with two or more separate binding sites that can bind to a single metallic central atom, forming a chelate.
Applications:
bone density conservation agent  An agent that inhibits bone resorption and/or favor bone mineralization and bone regeneration. Used to heal bone fractures and to treat bone diseases such as osteopenia and osteoporosis.
antineoplastic agent  A substance that inhibits or prevents the proliferation of neoplasms.
ChEBI Ontology
Outgoing Relation(s)
etidronic acid (CHEBI:4907) has role antineoplastic agent (CHEBI:35610)
etidronic acid (CHEBI:4907) has role bone density conservation agent (CHEBI:50646)
etidronic acid (CHEBI:4907) has role chelator (CHEBI:38161)
etidronic acid (CHEBI:4907) is a 1,1-bis(phosphonic acid) (CHEBI:77383)
etidronic acid (CHEBI:4907) is conjugate acid of etidronic acid(2−) (CHEBI:77356)
Incoming Relation(s)
etidronic acid(2−) (CHEBI:77356) is conjugate base of etidronic acid (CHEBI:4907)
IUPAC Name 
(1-hydroxyethane-1,1-diyl)bis(phosphonic acid)
INNs  Source
acide étidroniqueWHO MedNet
ácido etidrónicoWHO MedNet
acidum etidronicumDrugBank
etidronic acidKEGG DRUG
Synonyms  Source
1,1,1-Ethanetriol diphosphonateChemIDplus
1-Hydroxy-1,1-diphosphonoethaneChemIDplus
1-Hydroxyethane-1,1-bisphosphonic acidChemIDplus
1-Hydroxyethane-1,1-diphosphonateChemIDplus
1-Hydroxyethane-1,1-diphosphonic acidChemIDplus
1-Hydroxyethanediphosphonic acidChemIDplus
Manual XrefsDatabases
1098DrugCentral
911PDBeChem
C07736KEGG COMPOUND
D02373KEGG DRUG
DB01077DrugBank
Etidronic_acidWikipedia
HMDB0015210HMDB
LSM-5508LINCS
US3159581Patent
US3400147Patent
US3468935Patent
US3475486Patent
Registry NumbersSources
Reaxys:1789291Reaxys
CAS:2809-21-4KEGG COMPOUND
CAS:2809-21-4ChemIDplus
Citations