EMBL-EBI | Chemical Biology | ChEBI

Example searches: iron*, InChI=1S/CH4O/c1-2/h2H,1H3, caffeine | Advanced Search

CHEBI:4887 - ethosuximide

Default Structure
ChEBI IDCHEBI:4887
ChEBI Nameethosuximide
Stars
DefinitionA dicarboximide that is pyrrolidine-2,5-dione in which the hydrogens at position 3 are substituted by one methyl and one ethyl group. An antiepileptic, it is used in the treatment of absence seizures and may be used for myoclonic seizures, but is ineffective against tonic-clonic seizures.
Secondary ChEBI IDCHEBI:131811
Last Modified7 February 2023
DownloadsMolfile
FormulaC7H11NO2
Net Charge0
Average Mass141.170
Monoisotopic Mass141.07898
SMILESCCC1(C)CC(=O)NC1=O
InChIInChI=1S/C7H11NO2/c1-3-7(2)4-5(9)8-6(7)10/h3-4H2,1-2H3,(H,8,9,10)
InChIKeyHAPOVYFOVVWLRS-UHFFFAOYSA-N
Wikipedia
Roles Classification
Biological Roles:
T-type calcium channel blocker  Any agent that interferes with the activity of T-type calcium channels.
analgesic  An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms.
Applications:
antidepressant  Antidepressants are mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions.
anticonvulsant  A drug used to prevent seizures or reduce their severity.
antispasmodic drug  A drug that suppresses spasms. These are usually caused by smooth muscle contraction, especially in tubular organs. The effect is to prevent spasms of the stomach, intestine or urinary bladder.
geroprotector  Any compound that supports healthy aging, slows the biological aging process, or extends lifespan.
analgesic  An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms.
ChEBI Ontology
Outgoing Relation(s)
ethosuximide (CHEBI:4887) has role analgesic (CHEBI:35480)
ethosuximide (CHEBI:4887) has role anticonvulsant (CHEBI:35623)
ethosuximide (CHEBI:4887) has role antidepressant (CHEBI:35469)
ethosuximide (CHEBI:4887) has role antispasmodic drug (CHEBI:53784)
ethosuximide (CHEBI:4887) has role geroprotector (CHEBI:176497)
ethosuximide (CHEBI:4887) has role T-type calcium channel blocker (CHEBI:194338)
ethosuximide (CHEBI:4887) is a dicarboximide (CHEBI:35356)
ethosuximide (CHEBI:4887) is a pyrrolidinone (CHEBI:38275)
Incoming Relation(s)
(R)-ethosuximide (CHEBI:60354) is a ethosuximide (CHEBI:4887)
(S)-ethosuximide (CHEBI:60355) is a ethosuximide (CHEBI:4887)
IUPAC Name 
3-ethyl-3-methylpyrrolidine-2,5-dione
INNs  Source
ethosuximideChemIDplus
éthosuximideWHO MedNet
ethosuximidumChemIDplus
etosuximidaChemIDplus
Synonyms  Source
(±)-2-ethyl-2-methylsuccinimideChemIDplus
2-ethyl-2-methylsuccinimideChemIDplus
2-methyl-2-ethylsuccinimideChemIDplus
3-ethyl-3-methyl-2,5-pyrrolidinedioneChEBI
3-ethyl-3-methylsuccinimideChemIDplus
3-methyl-3-ethylpyrrolidine-2,5-dioneChemIDplus
Brand Names  Source
EmesideChEMBL
SuxinutinChEMBL
ZarontinChEMBL
Manual XrefsDatabases
1087DrugCentral
3175ChemSpider
C07505KEGG COMPOUND
D00539KEGG DRUG
DB00593DrugBank
EthosuximideWikipedia
HMDB0014731HMDB
LSM-5195LINCS
Registry NumbersSources
Reaxys:117054Reaxys
CAS:77-67-8NIST Chemistry WebBook
CAS:77-67-8KEGG COMPOUND
CAS:77-67-8ChemIDplus
Citations