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CHEBI:48280 - (R)-(+)-pindolol

Default Structure
ChEBI IDCHEBI:48280
ChEBI Name(R)-(+)-pindolol
Stars
ASCII Name(R)-(+)-pindolol
Last Modified17 December 2013
SubmitterKirill Degtyarenko
DownloadsMolfile
FormulaC14H20N2O2
Net Charge0
Average Mass248.326
Monoisotopic Mass248.15248
SMILESCC(C)NC[C@@H](O)COc1cccc2nccc12
InChIInChI=1S/C14H20N2O2/c1-10(2)16-8-11(17)9-18-14-5-3-4-13-12(14)6-7-15-13/h3-7,10-11,15-17H,8-9H2,1-2H3/t11-/m1/s1
InChIKeyJZQKKSLKJUAGIC-LLVKDONJSA-N
Roles Classification
Chemical Roles:
Bronsted base  A molecular entity capable of accepting a hydron from a donor (Brønsted acid).
Bronsted base  A molecular entity capable of accepting a hydron from a donor (Brønsted acid).
Biological Roles:
serotonergic antagonist  Drugs that bind to but do not activate serotonin receptors, thereby blocking the actions of serotonin or serotonergic agonists.
beta-adrenergic antagonist  An agent that binds to but does not activate β-adrenergic receptors thereby blocking the actions of endogenous or exogenous β-adrenergic agonists. β-Adrenergic antagonists are used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches and anxiety.
Applications:
vasodilator agent  A drug used to cause dilation of the blood vessels.
antihypertensive agent  Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism.
serotonergic antagonist  Drugs that bind to but do not activate serotonin receptors, thereby blocking the actions of serotonin or serotonergic agonists.
antiglaucoma drug  Any drug which can be used to prevent or alleviate glaucoma, a disease in which the optic nerve is damaged, resulting in progressive, irreversible loss of vision. It is often, though not always, associated with increased pressure of the fluid in the eye.
beta-adrenergic antagonist  An agent that binds to but does not activate β-adrenergic receptors thereby blocking the actions of endogenous or exogenous β-adrenergic agonists. β-Adrenergic antagonists are used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches and anxiety.
ChEBI Ontology
Outgoing Relation(s)
(R)-(+)-pindolol (CHEBI:48280) is a pindolol (CHEBI:8214)
(R)-(+)-pindolol (CHEBI:48280) is enantiomer of (S)-(−)-pindolol (CHEBI:48281)
Incoming Relation(s)
(S)-(−)-pindolol (CHEBI:48281) is enantiomer of (R)-(+)-pindolol (CHEBI:48280)
IUPAC Name 
(2R)-1-(1H-indol-4-yloxy)-3-[(propan-2-yl)amino]propan-2-ol
Synonyms  Source
(2R)-1-(1H-indol-4-yloxy)-3-((1-methylethyl)amino)-2-propanolChemIDplus
(2R)-1-(1H-indol-4-yloxy)-3-(isopropylamino)propan-2-olIUPAC
(R)-pindololChEBI
(+)-pindololChEBI
Registry NumbersSources
Beilstein:5747765Beilstein
Beilstein:5747767Beilstein
CAS:68374-35-6ChemIDplus