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CHEBI:4784 - enalapril
| Formula | C20H28N2O5 |
| Net Charge | 0 |
| Average Mass | 376.453 |
| Monoisotopic Mass | 376.19982 |
| SMILES | CCOC(=O)[C@H](CCc1ccccc1)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)O |
| InChI | InChI=1S/C20H28N2O5/c1-3-27-20(26)16(12-11-15-8-5-4-6-9-15)21-14(2)18(23)22-13-7-10-17(22)19(24)25/h4-6,8-9,14,16-17,21H,3,7,10-13H2,1-2H3,(H,24,25)/t14-,16-,17-/m0/s1 |
| InChIKey | GBXSMTUPTTWBMN-XIRDDKMYSA-N |
| Wikipedia |
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| Roles Classification |
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| Chemical Roles: | Bronsted acid A molecular entity capable of donating a hydron to an acceptor (Brønsted base). Bronsted base A molecular entity capable of accepting a hydron from a donor (Brønsted acid). |
| Biological Roles: | EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor An EC 3.4.15.* (peptidyl-dipeptidase) inhibitor that interferes with the action of peptidyl-dipeptidase A (EC 3.4.15.1). antiviral agent A substance that destroys or inhibits replication of viruses. antimicrobial agent A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans. |
| Applications: | EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor An EC 3.4.15.* (peptidyl-dipeptidase) inhibitor that interferes with the action of peptidyl-dipeptidase A (EC 3.4.15.1). hypoglycemic agent A drug which lowers the blood glucose level. antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. antihypertensive agent Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism. geroprotector Any compound that supports healthy aging, slows the biological aging process, or extends lifespan. vasodilator agent A drug used to cause dilation of the blood vessels. prodrug A compound that, on administration, must undergo chemical conversion by metabolic processes before becoming the pharmacologically active drug for which it is a prodrug. cardiovascular drug A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| enalapril (CHEBI:4784) has functional parent enalaprilat (anhydrous) (CHEBI:4786) |
| enalapril (CHEBI:4784) has role antihypertensive agent (CHEBI:35674) |
| enalapril (CHEBI:4784) has role antimicrobial agent (CHEBI:33281) |
| enalapril (CHEBI:4784) has role antineoplastic agent (CHEBI:35610) |
| enalapril (CHEBI:4784) has role antiviral agent (CHEBI:22587) |
| enalapril (CHEBI:4784) has role cardiovascular drug (CHEBI:35554) |
| enalapril (CHEBI:4784) has role EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor (CHEBI:35457) |
| enalapril (CHEBI:4784) has role geroprotector (CHEBI:176497) |
| enalapril (CHEBI:4784) has role hypoglycemic agent (CHEBI:35526) |
| enalapril (CHEBI:4784) has role prodrug (CHEBI:50266) |
| enalapril (CHEBI:4784) has role vasodilator agent (CHEBI:35620) |
| enalapril (CHEBI:4784) is a dicarboxylic acid monoester (CHEBI:36244) |
| enalapril (CHEBI:4784) is a dipeptide (CHEBI:46761) |
| Incoming Relation(s) |
| enalapril maleate (CHEBI:4785) has part enalapril (CHEBI:4784) |
| enalapril(1-) (CHEBI:760977) is conjugate base of enalapril (CHEBI:4784) |
| IUPAC Name |
|---|
| N-[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]-L-alanyl-L-proline |
| INNs | Source |
|---|---|
| ánalapril | WHO MedNet |
| enalapril | ChemIDplus |
| enalaprila | ChemIDplus |
| enalaprilum | ChemIDplus |
| Synonyms | Source |
|---|---|
| 1-(N-((S)-1-carboxy-3-phenylpropyl)-L-alanyl)-L-proline 1'-ethyl ester | ChemIDplus |
| C09AA02 | ChEMBL |
| Enalapril | KEGG COMPOUND |
| ENALAPRIL | ChEMBL |
| (S)-1-(N-(1-(ethoxycarbonyl)-3-phenylpropyl)-L-alanyl)-L-proline | ChemIDplus |
| Lexxel | ChEMBL |
| Citations |
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