ganciclovir (CHEBI:465284)

CHEBI:465284 - ganciclovir

ChEBI ID	CHEBI:465284
ChEBI Name	ganciclovir
Stars
Definition	An oxopurine that is guanine substituted by a [(1,3-dihydroxypropan-2-yl)oxy]methyl group at position 9. Ganciclovir is an antiviral drug used to treat or prevent AIDS-related cytomegalovirus infections.
Secondary ChEBI IDs	CHEBI:5273, CHEBI:42659
Last Modified	22 February 2017
Downloads	Molfile

Formula	C9H13N5O4
Net Charge	0
Average Mass	255.234
Monoisotopic Mass	255.09675
SMILES	Nc1nc(=O)c2ncn(COC(CO)CO)c2n1
InChI	InChI=1S/C9H13N5O4/c10-9-12-7-6(8(17)13-9)11-3-14(7)4-18-5(1-15)2-16/h3,5,15-16H,1-2,4H2,(H3,10,12,13,17)
InChIKey	IRSCQMHQWWYFCW-UHFFFAOYSA-N

Wikipedia

Roles Classification

anti-HIV agent An antiviral agent that destroys or inhibits the replication of the human immunodeficiency virus.

antiviral drug A substance used in the prophylaxis or therapy of virus diseases.

antiviral agent A substance that destroys or inhibits replication of viruses.

antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms.

hypoglycemic agent A drug which lowers the blood glucose level.

ophthalmology drug Any compound used for the treatment of eye conditions or eye diseases.

renoprotective agent Any compound that is able to prevent damage to the kidneys.

antiviral drug A substance used in the prophylaxis or therapy of virus diseases.

antiinfective agent A substance used in the prophylaxis or therapy of infectious diseases.

ChEBI Ontology

Outgoing Relation(s)
	ganciclovir (CHEBI:465284) has functional parent guanine (CHEBI:16235)
	ganciclovir (CHEBI:465284) has role anti-HIV agent (CHEBI:64946)
	ganciclovir (CHEBI:465284) has role antiinfective agent (CHEBI:35441)
	ganciclovir (CHEBI:465284) has role antineoplastic agent (CHEBI:35610)
	ganciclovir (CHEBI:465284) has role antiviral agent (CHEBI:22587)
	ganciclovir (CHEBI:465284) has role antiviral drug (CHEBI:36044)
	ganciclovir (CHEBI:465284) has role hypoglycemic agent (CHEBI:35526)
	ganciclovir (CHEBI:465284) has role ophthalmology drug (CHEBI:66981)
	ganciclovir (CHEBI:465284) has role renoprotective agent (CHEBI:231911)
	ganciclovir (CHEBI:465284) is a 2-aminopurines (CHEBI:20702)
	ganciclovir (CHEBI:465284) is a oxopurine (CHEBI:25810)
Incoming Relation(s)
Incoming Relation(s)	valganciclovir (CHEBI:63635) has functional parent ganciclovir (CHEBI:465284)

IUPAC Name
2-amino-9-{[(1,3-dihydroxypropan-2-yl)oxy]methyl}-1,9-dihydro-6H-purin-6-one

INN	Source
ganciclovir	KEGG DRUG

Synonyms	Source
2-(6-Amino-purin-9-ylmethoxy)-propane-1,3-diol	ChEMBL
2-amino-9-((1,3-dihydroxypropan-2-yloxy)methyl)-1H-purin-6(9H)-one	ChEMBL
2-amino-9-((1,3-dihydroxypropan-2-yloxy)methyl)-3H-purin-6(9H)-one	ChEMBL
2-amino-9-((1,3-dihydroxypropan-2-yloxy)methyl)-9H-purin-6-ol	ChEMBL
2-Amino-9-(2-hydroxy-1-hydroxymethyl-ethoxymethyl)-1,9-dihydro-purin-6-one	ChEMBL
2-amino-9-(2-hydroxy-1-hydroxymethylethoxymethyl)-6,9-dihydro-1H-6-purinone	ChEMBL

Citations