ganciclovir (CHEBI:465284)

CHEBI:465284 - ganciclovir

ChEBI ID	CHEBI:465284
ChEBI Name	ganciclovir
Stars
Definition	An oxopurine that is guanine substituted by a [(1,3-dihydroxypropan-2-yl)oxy]methyl group at position 9. Ganciclovir is an antiviral drug used to treat or prevent AIDS-related cytomegalovirus infections.
Secondary ChEBI IDs	CHEBI:5273, CHEBI:42659
Last Modified	22 February 2017
Downloads	Molfile

Formula	C9H13N5O4
Net Charge	0
Average Mass	255.234
Monoisotopic Mass	255.09675
SMILES	Nc1nc(=O)c2ncn(COC(CO)CO)c2n1
InChI	InChI=1S/C9H13N5O4/c10-9-12-7-6(8(17)13-9)11-3-14(7)4-18-5(1-15)2-16/h3,5,15-16H,1-2,4H2,(H3,10,12,13,17)
InChIKey	IRSCQMHQWWYFCW-UHFFFAOYSA-N

Wikipedia

Roles Classification

anti-HIV agent An antiviral agent that destroys or inhibits the replication of the human immunodeficiency virus.

antiviral agent A substance that destroys or inhibits replication of viruses.

antiviral drug A substance used in the prophylaxis or therapy of virus diseases.

antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms.

antiinfective agent A substance used in the prophylaxis or therapy of infectious diseases.

ophthalmology drug Any compound used for the treatment of eye conditions or eye diseases.

antiviral drug A substance used in the prophylaxis or therapy of virus diseases.

renoprotective agent Any compound that is able to prevent damage to the kidneys.

hypoglycemic agent A drug which lowers the blood glucose level.

ChEBI Ontology

Outgoing Relation(s)
	ganciclovir (CHEBI:465284) has functional parent guanine (CHEBI:16235)
	ganciclovir (CHEBI:465284) has role anti-HIV agent (CHEBI:64946)
	ganciclovir (CHEBI:465284) has role antiinfective agent (CHEBI:35441)
	ganciclovir (CHEBI:465284) has role antineoplastic agent (CHEBI:35610)
	ganciclovir (CHEBI:465284) has role antiviral agent (CHEBI:22587)
	ganciclovir (CHEBI:465284) has role antiviral drug (CHEBI:36044)
	ganciclovir (CHEBI:465284) has role hypoglycemic agent (CHEBI:35526)
	ganciclovir (CHEBI:465284) has role ophthalmology drug (CHEBI:66981)
	ganciclovir (CHEBI:465284) has role renoprotective agent (CHEBI:231911)
	ganciclovir (CHEBI:465284) is a 2-aminopurines (CHEBI:20702)
	ganciclovir (CHEBI:465284) is a oxopurine (CHEBI:25810)
Incoming Relation(s)
Incoming Relation(s)	valganciclovir (CHEBI:63635) has functional parent ganciclovir (CHEBI:465284)

IUPAC Name
2-amino-9-{[(1,3-dihydroxypropan-2-yl)oxy]methyl}-1,9-dihydro-6H-purin-6-one

INN	Source
ganciclovir	KEGG DRUG

Synonyms	Source
2-(6-Amino-purin-9-ylmethoxy)-propane-1,3-diol	ChEMBL
2-amino-9-((1,3-dihydroxypropan-2-yloxy)methyl)-1H-purin-6(9H)-one	ChEMBL
2-amino-9-((1,3-dihydroxypropan-2-yloxy)methyl)-3H-purin-6(9H)-one	ChEMBL
2-amino-9-((1,3-dihydroxypropan-2-yloxy)methyl)-9H-purin-6-ol	ChEMBL
2-Amino-9-(2-hydroxy-1-hydroxymethyl-ethoxymethyl)-1,9-dihydro-purin-6-one	ChEMBL
2-amino-9-(2-hydroxy-1-hydroxymethylethoxymethyl)-6,9-dihydro-1H-6-purinone	ChEMBL

Citations