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CHEBI:41423 - celecoxib
| Formula | C17H14F3N3O2S |
| Net Charge | 0 |
| Average Mass | 381.379 |
| Monoisotopic Mass | 381.07588 |
| SMILES | Cc1ccc(-c2cc(C(F)(F)F)nn2-c2ccc(S(N)(=O)=O)cc2)cc1 |
| InChI | InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25) |
| InChIKey | RZEKVGVHFLEQIL-UHFFFAOYSA-N |
| Wikipedia |
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| Roles Classification |
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| Biological Roles: | antiviral agent A substance that destroys or inhibits replication of viruses. anti-obesity agent Any substance which is used to reduce or control weight. anticoronaviral agent Any antiviral agent which inhibits the activity of coronaviruses. analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. immunosuppressive agent An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response. cyclooxygenase 2 inhibitor A cyclooxygenase inhibitor that interferes with the action of cyclooxygenase 2. anti-HBV agent An antiviral agent that destroys or inhibits the replication of the hepatitis B virus. non-narcotic analgesic A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors. antitubercular agent A substance that kills or slows the growth of Mycobacterium tuberculosis and is used in the treatment of tuberculosis. |
| Applications: | vulnerary A drug used in treating and healing of wounds. anti-inflammatory agent Any compound that has anti-inflammatory effects. geroprotector Any compound that supports healthy aging, slows the biological aging process, or extends lifespan. antihypertensive agent Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism. analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. immunosuppressive agent An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response. anti-ulcer drug One of various classes of drugs with different action mechanisms used to treat or ameliorate peptic ulcer or irritation of the gastrointestinal tract. antidepressant Antidepressants are mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. antirheumatic drug A drug used to treat rheumatoid arthritis. antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. non-steroidal anti-inflammatory drug An anti-inflammatory drug that is not a steroid. In addition to anti-inflammatory actions, non-steroidal anti-inflammatory drugs have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. ophthalmology drug Any compound used for the treatment of eye conditions or eye diseases. vasoconstrictor agent Drug used to cause constriction of the blood vessels. non-narcotic analgesic A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors. antitubercular agent A substance that kills or slows the growth of Mycobacterium tuberculosis and is used in the treatment of tuberculosis. antipsychotic agent Antipsychotic drugs are agents that control agitated psychotic behaviour, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect. gout suppressant A drug that increases uric acid excretion by the kidney (uricosuric drug), decreases uric acid production (antihyperuricemic), or alleviates the pain and inflammation of acute attacks of gout. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| celecoxib (CHEBI:41423) has role analgesic (CHEBI:35480) |
| celecoxib (CHEBI:41423) has role anti-HBV agent (CHEBI:64951) |
| celecoxib (CHEBI:41423) has role anti-inflammatory agent (CHEBI:67079) |
| celecoxib (CHEBI:41423) has role anti-obesity agent (CHEBI:74518) |
| celecoxib (CHEBI:41423) has role anti-ulcer drug (CHEBI:49201) |
| celecoxib (CHEBI:41423) has role anticoronaviral agent (CHEBI:149553) |
| celecoxib (CHEBI:41423) has role antidepressant (CHEBI:35469) |
| celecoxib (CHEBI:41423) has role antihypertensive agent (CHEBI:35674) |
| celecoxib (CHEBI:41423) has role antineoplastic agent (CHEBI:35610) |
| celecoxib (CHEBI:41423) has role antipsychotic agent (CHEBI:35476) |
| celecoxib (CHEBI:41423) has role antirheumatic drug (CHEBI:35842) |
| celecoxib (CHEBI:41423) has role antitubercular agent (CHEBI:33231) |
| celecoxib (CHEBI:41423) has role antiviral agent (CHEBI:22587) |
| celecoxib (CHEBI:41423) has role cyclooxygenase 2 inhibitor (CHEBI:50629) |
| celecoxib (CHEBI:41423) has role geroprotector (CHEBI:176497) |
| celecoxib (CHEBI:41423) has role gout suppressant (CHEBI:35845) |
| celecoxib (CHEBI:41423) has role immunosuppressive agent (CHEBI:35705) |
| celecoxib (CHEBI:41423) has role non-narcotic analgesic (CHEBI:35481) |
| celecoxib (CHEBI:41423) has role non-steroidal anti-inflammatory drug (CHEBI:35475) |
| celecoxib (CHEBI:41423) has role ophthalmology drug (CHEBI:66981) |
| celecoxib (CHEBI:41423) has role vasoconstrictor agent (CHEBI:50514) |
| celecoxib (CHEBI:41423) has role vulnerary (CHEBI:73336) |
| celecoxib (CHEBI:41423) is a organofluorine compound (CHEBI:37143) |
| celecoxib (CHEBI:41423) is a pyrazoles (CHEBI:26410) |
| celecoxib (CHEBI:41423) is a sulfonamide (CHEBI:35358) |
| celecoxib (CHEBI:41423) is a toluenes (CHEBI:27024) |
| IUPAC Name |
|---|
| 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide |
| INNs | Source |
|---|---|
| celecoxib | WHO MedNet |
| celecoxib | WHO MedNet |
| célécoxib | WHO MedNet |
| celecoxibum | WHO MedNet |
| Synonyms | Source |
|---|---|
| Celecoxib | KEGG COMPOUND |
| DFN-15 | ChEMBL |
| DFN15 | ChEMBL |
| NSC-719627 | ChEMBL |
| NSC-758624 | ChEMBL |
| p-(5-p-Tolyl-3-(trifluoromethyl)pyrazol-1-yl)benzenesulfonamide | ChemIDplus |
| Brand Names | Source |
|---|---|
| Celebra | ChEMBL |
| Celebrex | KEGG DRUG |
| Celecoxib component of consensi | ChEMBL |
| Celecoxib component of seglentis | ChEMBL |
| Elyxyb | ChEMBL |
| Registry Numbers | Sources |
|---|---|
| Reaxys:8280770 | Reaxys |
| CAS:169590-42-5 | ChemIDplus |
| CAS:169590-42-5 | NIST Chemistry WebBook |
| CAS:184007-95-2 | ChemIDplus |
| Citations |
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