EMBL-EBI | Chemical Biology | ChEBI
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| ChEBI ID | CHEBI:4025 |
| ChEBI Name | cyclopentolate hydrochloride |
| Stars | |
| Definition | The hydrochloride salt of cyclopentolate. It is used to produce mydriasis (excessive dilation of the pupil) and cycloplegia (paralysis of the ciliary muscle of the eye) for opthalmic diagnostic procedures. It acts more quickly than atropine and has a shorter duration of action. |
| Last Modified | 30 June 2010 |
| Wikipedia |
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| Roles Classification |
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| Biological Roles: | muscarinic antagonist A drug that binds to but does not activate muscarinic cholinergic receptors, thereby blocking the actions of endogenous acetylcholine or exogenous agonists. parasympatholytic Any cholinergic antagonist that inhibits the actions of the parasympathetic nervous system. The major group of drugs used therapeutically for this purpose is the muscarinic antagonists. |
| Applications: | diagnostic agent A substance administered to aid diagnosis of a disease. mydriatic agent Agent that dilates the pupil. Used in eye diseases and to facilitate eye examination. It may be either a sympathomimetic or parasympatholytic. The latter cause cycloplegia or paralysis of accommodation at high doses and may precipitate glaucoma. muscarinic antagonist A drug that binds to but does not activate muscarinic cholinergic receptors, thereby blocking the actions of endogenous acetylcholine or exogenous agonists. parasympatholytic Any cholinergic antagonist that inhibits the actions of the parasympathetic nervous system. The major group of drugs used therapeutically for this purpose is the muscarinic antagonists. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| cyclopentolate hydrochloride (CHEBI:4025) has part cyclopentolate (CHEBI:4024) |
| cyclopentolate hydrochloride (CHEBI:4025) has role diagnostic agent (CHEBI:33295) |
| cyclopentolate hydrochloride (CHEBI:4025) has role muscarinic antagonist (CHEBI:48876) |
| cyclopentolate hydrochloride (CHEBI:4025) has role mydriatic agent (CHEBI:50513) |
| cyclopentolate hydrochloride (CHEBI:4025) has role parasympatholytic (CHEBI:50370) |
| cyclopentolate hydrochloride (CHEBI:4025) is a hydrochloride (CHEBI:36807) |
| Incoming Relation(s) |
| (R)-cyclopentolate hydrochloride (CHEBI:59690) is a cyclopentolate hydrochloride (CHEBI:4025) |
| (S)-cyclopentolate hydrochloride (CHEBI:59691) is a cyclopentolate hydrochloride (CHEBI:4025) |
| IUPAC Name |
|---|
| 2-(dimethylamino)ethyl (1-hydroxycyclopentyl)(phenyl)acetate hydrochloride |
| Synonyms | Source |
|---|---|
| cyclopentolate HCl | ChemIDplus |
| β-dimethylaminoethyl (1-hydroxycyclopentyl)phenylacetate hydrochloride | ChemIDplus |
| 2-(dimethylamino)ethyl 1-hydroxy-α-phenylcyclopentaneacetate hydrochloride | ChemIDplus |
| 2-(dimethylamino)ethyl (±)-1-hydroxy-α-phenylcyclopentaneacetate hydrochloride | ChemIDplus |
| (±)-cyclopentolate HCl | ChEBI |
| Manual Xrefs | Databases |
|---|---|
| D01002 | KEGG DRUG |
| DB00979 | DrugBank |
| Cyclopentolate | Wikipedia |
| Registry Numbers | Sources |
|---|---|
| Beilstein:3760509 | Beilstein |
| CAS:5870-29-1 | ChemIDplus |
| CAS:5870-29-1 | KEGG DRUG |