sunitinib (CHEBI:38940)

CHEBI:38940 - sunitinib

Formula	C22H27FN4O2
Net Charge	0
Average Mass	398.482
Monoisotopic Mass	398.21180
SMILES	CCN(CC)CCNC(=O)c1c(C)nc(/C=C2\C(=O)Nc3ccc(F)cc32)c1C
InChI	InChI=1S/C22H27FN4O2/c1-5-27(6-2)10-9-24-22(29)20-13(3)19(25-14(20)4)12-17-16-11-15(23)7-8-18(16)26-21(17)28/h7-8,11-12,25H,5-6,9-10H2,1-4H3,(H,24,29)(H,26,28)/b17-12-
InChIKey	WINHZLLDWRZWRT-ATVHPVEESA-N

Wikipedia

Roles Classification

antiviral agent A substance that destroys or inhibits replication of viruses.

vascular endothelial growth factor receptor antagonist An antagonist at the vascular endothelial growth factor receptor.

EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor An EC 2.7.10.* (protein-tyrosine kinase) inhibitor that interferes with the action of receptor protein-tyrosine kinase (EC 2.7.10.1).

immunomodulator Biologically active substance whose activity affects or plays a role in the functioning of the immune system.

neuroprotective agent Any compound that can be used for the treatment of neurodegenerative disorders.

renoprotective agent Any compound that is able to prevent damage to the kidneys.

antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms.

angiogenesis inhibitor An agent and endogenous substances that antagonize or inhibit the development of new blood vessels.

immunomodulator Biologically active substance whose activity affects or plays a role in the functioning of the immune system.

ChEBI Ontology

Outgoing Relation(s)
	sunitinib (CHEBI:38940) has functional parent 3-methyleneoxindole (CHEBI:17920)
	sunitinib (CHEBI:38940) has role angiogenesis inhibitor (CHEBI:48422)
	sunitinib (CHEBI:38940) has role antineoplastic agent (CHEBI:35610)
	sunitinib (CHEBI:38940) has role antiviral agent (CHEBI:22587)
	sunitinib (CHEBI:38940) has role EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor (CHEBI:62434)
	sunitinib (CHEBI:38940) has role immunomodulator (CHEBI:50846)
	sunitinib (CHEBI:38940) has role neuroprotective agent (CHEBI:63726)
	sunitinib (CHEBI:38940) has role renoprotective agent (CHEBI:231911)
	sunitinib (CHEBI:38940) has role vascular endothelial growth factor receptor antagonist (CHEBI:65207)
	sunitinib (CHEBI:38940) is a monocarboxylic acid amide (CHEBI:29347)
	sunitinib (CHEBI:38940) is a pyrroles (CHEBI:26455)
Incoming Relation(s)
	linkable sunitinib analogue (CHEBI:39081) has functional parent sunitinib (CHEBI:38940)
	sunitinib malate (CHEBI:232546) has part sunitinib (CHEBI:38940)

IUPAC Name
N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide

INNs	Source
sunitinib	ChEBI
sunitinibum	ChEBI

Brand Name	Source
Sunitinib accord	ChEMBL

Registry Numbers	Sources
CAS:557795-19-4	ChemIDplus

Citations